7-Hydroxy-3,4-dihydro-2(1H)-quinolinone, identified by CAS number 22246-18-0, is a significant organic compound with established utility in the pharmaceutical industry. Its primary role as an intermediate in the synthesis of Aripiprazole, a groundbreaking antipsychotic medication, underscores its importance. For professionals seeking to purchase this compound, a thorough understanding of its chemical properties and applications is essential.

Chemically, 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is characterized by its molecular formula C9H9NO2 and a molecular weight of 163.173 g/mol. It typically presents as an off-white powder, with a melting point range of 233-237 °C. This solid form and specific melting point are key quality indicators often detailed by manufacturers and suppliers. Its solubility in common organic solvents like DMSO and methanol, though sometimes described as slight, is sufficient for many synthetic processes.

The critical application driving demand for this intermediate is its indispensable role in the production of Aripiprazole. Pharmaceutical companies worldwide rely on a consistent supply of high-purity 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone to ensure the quality and efficacy of their final drug products. Sourcing this intermediate from reputable manufacturers in China offers a strategic advantage in terms of cost-effectiveness and availability. When you search for '7-hydroxy-3,4-dihydro-2(1H)-quinolinone price' or 'Aripiprazole intermediate supplier,' focus on providers that emphasize batch consistency and rigorous quality control.

Beyond its established pharmaceutical use, research has indicated other potential applications for 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone. It has been identified as a compound with antitumor activity and as a hydroxyindole analog inhibitor of tyrosinase melanoma. These findings suggest its value in broader pharmaceutical research and development, potentially opening avenues for new therapeutic agents. For research institutions, obtaining this compound through reliable chemical suppliers is crucial for experimental integrity.

When procuring 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone, look for suppliers who can provide detailed specifications and regulatory support. The availability of a Certificate of Analysis (CoA) confirming its purity (typically ≥98.0%) and a Material Safety Data Sheet (MSDS) are standard requirements. Furthermore, understanding the competitive landscape of suppliers and manufacturers in China can help in negotiating favorable terms for bulk purchases. Investing in a reliable supply chain for this intermediate is a strategic decision that supports both current production needs and future research endeavors.

In summary, 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a cornerstone intermediate in the pharmaceutical synthesis of Aripiprazole. Its well-defined chemical properties and emerging therapeutic potential make it a compound of significant interest. By diligently researching and engaging with trusted manufacturers and suppliers, professionals can secure a high-quality and cost-effective source for this vital chemical.