In the realm of fine chemicals and pharmaceutical intermediates, understanding the fundamental properties and diverse applications of key compounds is crucial for scientific advancement and industrial success. 8-Hydroxyquinoline-2-Carboxylic Acid (CAS: 1571-30-8) is a compound that has garnered significant attention due to its versatile chemical nature and its utility in various synthesis pathways.

Chemical Identity and Physical Properties

8-Hydroxyquinoline-2-Carboxylic Acid, also known by synonyms such as 8-hydroxyquinaldic acid, is a heterocyclic organic compound. Its molecular formula is C10H7NO3, with a molecular weight of approximately 189.17 g/mol. Typically presenting as a yellow crystalline powder, it possesses a melting point in the range of 213-214 °C. Its chemical structure features a quinoline ring system with a hydroxyl group at the 8-position and a carboxylic acid group at the 2-position. This arrangement makes it a tridentate chelating agent, capable of forming stable complexes with metal ions. These properties are fundamental for its application in various chemical processes.

Key Applications and Synthesis Roles

The primary utility of 8-Hydroxyquinoline-2-Carboxylic Acid lies in its role as a versatile building block and intermediate in organic synthesis, particularly within the pharmaceutical industry. Its structure allows for a range of chemical transformations, making it valuable for creating more complex molecules. Key application areas include:

  • Pharmaceutical Intermediates: It is a crucial precursor in the synthesis of various Active Pharmaceutical Ingredients (APIs). R&D scientists and formulation chemists rely on this compound to construct specific molecular scaffolds that impart desired therapeutic properties. When looking to buy this material for pharmaceutical applications, ensuring high purity (often 95% or 98%) from a reliable manufacturer is paramount.
  • Organic Synthesis: Beyond pharmaceuticals, it serves as a general organic building block for synthesizing novel heterocyclic compounds, dyes, and specialty chemicals. Its reactivity makes it amenable to various coupling reactions and derivatizations.
  • Coordination Chemistry: As a chelating agent, it finds applications in coordination chemistry, used in the preparation of metal complexes that may have catalytic or material science properties.

Sourcing and Availability

Procuring high-quality 8-Hydroxyquinoline-2-Carboxylic Acid requires partnering with dependable chemical suppliers. Many organizations purchase this compound from specialized chemical manufacturers and distributors, with a significant number of these suppliers located in China. These Chinese manufacturers often offer competitive price points, especially for bulk orders, alongside robust production capabilities. When evaluating a supplier, it’s vital to verify their adherence to quality standards, check for comprehensive product specifications (including CAS number: 1571-30-8), and obtain samples for validation.

For those seeking to buy this essential chemical, engaging with suppliers who can provide consistent purity, timely delivery, and thorough documentation like Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS) is key to successful research and manufacturing outcomes.