Antazoline Hydrochloride (CAS 2508-72-7) is a well-established pharmaceutical intermediate recognized for its potent antihistamine properties. Primarily known for its role in treating ocular allergies, such as allergic conjunctivitis, this compound acts as a histamine H1 receptor blocker. For researchers, formulators, and procurement managers in the pharmaceutical industry, a thorough understanding of its uses, chemical properties, and where to procure it reliably is essential.

The primary therapeutic application of Antazoline Hydrochloride is its use in ophthalmic preparations to relieve symptoms like itching, redness, and inflammation of the eyes caused by allergic reactions. Its mechanism involves antagonizing the action of histamine at H1 receptors, thereby preventing the cascade of allergic responses. Beyond its antihistaminic function, it is also noted for its potential as an imidazoline binding site ligand, suggesting broader research avenues in pharmacology.

Chemically, Antazoline Hydrochloride is characterized by its molecular formula C17H20ClN3 and a molecular weight of 301.81. It presents as a white to off-white solid and has a melting point of 238°C. Its solubility in specific solvents like DMSO (slightly, when heated) and methanol (slightly) is important information for laboratory use and formulation development. When considering a purchase, it is crucial to obtain detailed specifications from potential suppliers.

For businesses looking to buy Antazoline Hydrochloride, identifying a trustworthy manufacturer or supplier is key. China hosts numerous chemical manufacturers that offer this intermediate. When evaluating potential suppliers, consider factors such as their production capacity, adherence to quality management systems (like ISO certification), and the availability of detailed Certificates of Analysis (CoA). A strong supplier relationship can ensure a consistent supply, competitive pricing, and valuable technical support.

When initiating contact with a supplier for Antazoline Hydrochloride, be prepared to discuss your specific requirements, including the quantity needed and any particular purity standards. Requesting a price quotation and samples is a standard part of the procurement process. This allows formulators to verify the material's suitability for their intended application and confirm its performance characteristics. Establishing a dialogue with a supplier can also provide insights into market availability and potential future supply trends.

In summary, Antazoline Hydrochloride is a vital pharmaceutical intermediate for antihistamine formulations, especially in ophthalmology. By understanding its properties and applications and by diligently selecting reliable suppliers, especially from China, companies can ensure the quality and availability of this critical compound, supporting their drug development and manufacturing goals effectively.