Understanding Benzene Metabolites: The Role of 1,2,4-Benzenetriol in Toxicological Research
The study of toxicology often involves understanding how the body processes and reacts to harmful substances. Benzene, a common industrial solvent and component of gasoline, is a known human carcinogen, and its metabolic pathways are of significant interest. Among its various metabolites, 1,2,4-Benzenetriol (CAS 533-73-3) plays a critical role in understanding benzene's toxicity. Researchers often need to buy high-purity samples for their studies, making it important to know its significance and where to source it reliably.
1,2,4-Benzenetriol: A Key Benzene Metabolite
When benzene is introduced into the body, it undergoes a series of enzymatic transformations. One of the key metabolic products is 1,2,4-Benzenetriol (molecular formula C₆H₆O₃), also known as hydroxyhydroquinone. This compound is formed through the hydroxylation of benzene and its other metabolites. Research indicates that 1,2,4-Benzenetriol, along with other phenolic metabolites, can contribute to the hematotoxicity and carcinogenicity associated with benzene exposure. It is implicated in inducing DNA damage and oxidative stress within cells, mechanisms that are central to its toxicological profile.
Research Applications and Sourcing Needs
Toxicologists and researchers studying the effects of benzene exposure require pure samples of its metabolites, including 1,2,4-Benzenetriol, for in vitro and in vivo experiments. These studies aim to elucidate the specific mechanisms by which benzene causes harm, identify biomarkers of exposure, and develop preventive strategies.
When purchasing 1,2,4-Benzenetriol for research purposes, consider the following:
- Purity: High purity is essential for accurate experimental results. Ensure the supplier provides detailed analytical data.
- Availability: Access to a consistent supply is crucial for ongoing research projects.
- Supplier Trustworthiness: Partnering with a reputable chemical supplier, particularly one known for its fine chemicals and pharmaceutical intermediates, guarantees product quality and reliability.
Trusted Supplier for Research Chemicals
As a leading manufacturer and supplier of fine chemicals in China, we provide high-purity 1,2,4-Benzenetriol (CAS 533-73-3) that meets the stringent requirements of toxicological research. We understand the importance of quality and consistency for scientific studies. If your research requires this vital benzene metabolite, we are your trusted source. Contact us to inquire about pricing, bulk availability, and to ensure you have a reliable supply for your critical research needs.
Perspectives & Insights
Future Origin 2025
“Benzene, a common industrial solvent and component of gasoline, is a known human carcinogen, and its metabolic pathways are of significant interest.”
Core Analyst 01
“Among its various metabolites, 1,2,4-Benzenetriol (CAS 533-73-3) plays a critical role in understanding benzene's toxicity.”
Silicon Seeker One
“Researchers often need to buy high-purity samples for their studies, making it important to know its significance and where to source it reliably.”