In the pharmaceutical industry, understanding the precise properties and applications of key chemical intermediates is crucial for innovation and production. Bexarotene, identified by its CAS number 153559-49-0, is a significant synthetic retinoid compound that holds considerable importance in the development of targeted therapies, particularly for oncological applications.

Bexarotene operates as a selective activator of retinoid X receptor (RXR) subtypes. This action influences gene expression that governs cellular differentiation and proliferation, making it a potent agent in the treatment of diseases like Cutaneous T-cell Lymphoma (CTCL). For pharmaceutical scientists and R&D teams, this specific mechanism highlights Bexarotene's value as a pharmaceutical intermediate in creating advanced treatment protocols.

The typical form of Bexarotene used in synthesis is a white solid, with high purity being a critical requirement for pharmaceutical-grade material. When procuring Bexarotene, professionals should look for suppliers who can guarantee a minimum purity of 99%. Information regarding its molecular formula (C24H28O2) and molecular weight (348.48) is also vital for accurate formulation and synthesis planning.

A key aspect for any professional involved in sourcing this pharmaceutical intermediate is understanding its supply chain. Identifying reliable manufacturers, especially those based in China, who can provide consistent quality and competitive pricing is a strategic advantage. Potential buyers should always request detailed Certificates of Analysis (CoAs) for each batch to ensure it meets stringent quality standards. Furthermore, understanding the lead times and minimum order quantities (MOQs) from a supplier is essential for production planning.

While the therapeutic application of Bexarotene involves managing side effects like lipid abnormalities and hypothyroidism, the focus for intermediate sourcing is on the product's intrinsic qualities. Professionals in the pharmaceutical sector looking to buy Bexarotene should prioritize suppliers who demonstrate a strong commitment to quality control, regulatory compliance, and customer service. Exploring options from reputable manufacturers ensures that your research and production pipelines are supported by dependable, high-quality pharmaceutical intermediates.