For professionals in chemical synthesis, pharmaceutical research, and biotechnology, the precise nature of chemical building blocks dictates the success of their endeavors. Boc-D-Phenylalaninol, a protected amino alcohol, is one such critical compound. Its unique characteristics make it highly valuable, particularly in the demanding field of peptide synthesis. This article explores the properties, synthesis considerations, and the importance of sourcing high-quality Boc-D-Phenylalaninol, especially from reputable manufacturers and suppliers in China.

Boc-D-Phenylalaninol is characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the amino moiety of D-phenylalaninol. This Boc group is essential for controlled synthesis, especially in Solid Phase Peptide Synthesis (SPPS) that utilizes the Boc strategy. The 'D' designation refers to the stereochemistry of the alpha-carbon, indicating the D-enantiomer of phenylalanine. This stereochemical detail is vital, as the biological and chemical properties of peptides can be significantly altered by the inclusion of D-amino acids.

Chemically, Boc-D-Phenylalaninol is typically presented as a white crystalline powder. Its molecular formula is C14H21NO3, with a molecular weight of approximately 251.3 g/mol. The Boc group renders the compound stable under neutral and basic conditions, but it can be readily cleaved by mild acidic treatments, such as trifluoroacetic acid (TFA). This ease of deprotection is a key advantage in multi-step synthesis processes. For researchers looking to buy Boc-D-Phenylalaninol, understanding these properties is crucial for optimizing reaction conditions and purification strategies.

The synthesis of Boc-D-Phenylalaninol typically involves the protection of the amino group of D-phenylalaninol with a Boc-introducing reagent, such as di-tert-butyl dicarbonate (Boc anhydride). This reaction is usually carried out in a suitable solvent system, often in the presence of a base to neutralize the acid by-product. The purification steps following synthesis are critical to achieve the high purity levels required for pharmaceutical applications and research.

When sourcing this compound, the quality and reliability of the Boc-D-Phenylalaninol manufacturer and supplier are paramount. For laboratories and companies engaged in cutting-edge research, consistent purity and enantiomeric excess are non-negotiable. A trusted supplier will provide detailed specifications, including purity by HPLC, optical rotation data, and a Certificate of Analysis (CoA) for each batch. The Boc-D-Phenylalaninol price should be considered in conjunction with these quality assurances. Sourcing from a reputable Boc-D-Phenylalaninol supplier in China can offer a balance of quality and cost-effectiveness.

In conclusion, Boc-D-Phenylalaninol is a fundamental building block for advanced organic synthesis, particularly in the burgeoning field of peptide therapeutics. Its specific chemical structure, protective group strategy, and stereochemistry make it indispensable for custom peptide synthesis and drug discovery. By prioritizing high-purity materials from reliable manufacturers, researchers can ensure the success and reproducibility of their critical R&D projects.