In the realm of advanced chemical synthesis and research, understanding the properties and applications of specialized reagents is crucial. Boc-D-Thz-OH, a protected amino acid derivative, is one such compound that plays a significant role in peptide synthesis and medicinal chemistry. This article provides an overview of Boc-D-Thz-OH, covering its key characteristics, uses, and guidance on sourcing it effectively.

Boc-D-Thz-OH, scientifically referred to as N-Boc-D-thiazolidine-4-carboxylic acid, is identified by its CAS number 63091-82-7. Its molecular formula is C9H15NO4S, with a molecular weight of approximately 233.28 g/mol. Typically appearing as a white crystalline powder, this compound is valued for its Boc protecting group, which facilitates controlled chemical reactions, and its inherent thiazolidine ring structure. This unique combination allows for the construction of peptides with modified properties, often leading to enhanced stability or altered biological activity compared to peptides made from standard amino acids.

The primary application of Boc-D-Thz-OH lies in peptide synthesis, where it serves as a building block for creating complex peptide sequences. Researchers in fields such as drug discovery and biochemical research utilize this compound to develop novel therapeutic agents, explore structure-activity relationships, and engineer peptides with specific functionalities. Its use can be critical in designing peptidomimetics or cyclic peptides that exhibit improved pharmacokinetic profiles.

For professionals looking to buy Boc-D-Thz-OH, several factors are important. Firstly, purity is key; a high-purity grade (e.g., ≥99% by HPLC) ensures reliable experimental results. Secondly, consistent availability from a reputable supplier or manufacturer is essential for ongoing research projects. Many laboratories seek out companies that offer competitive pricing for bulk orders, making this specialized intermediate more accessible.

When sourcing Boc-D-Thz-OH, it is beneficial to consider suppliers who specialize in amino acid derivatives and peptide synthesis reagents. These suppliers often have robust quality control systems in place and can provide comprehensive technical documentation, such as Safety Data Sheets (SDS) and Certificates of Analysis (COA). Exploring options from established chemical distributors or direct manufacturers, including those based in regions like China, can offer a broad selection and varied price points.

In summary, Boc-D-Thz-OH is a valuable chemical intermediate with significant applications in peptide synthesis and medicinal chemistry. Understanding its properties and where to source it reliably is vital for researchers aiming to innovate in these fields. Prioritizing purity, consistent supply, and competitive pricing when looking to purchase this compound will contribute to the success of your research endeavors.