Understanding Boc-L-Isoleucine (CAS 13139-16-7): Properties and Applications in Research
For researchers delving into molecular biology, biochemistry, and medicinal chemistry, understanding the properties and applications of key reagents is essential. Boc-L-Isoleucine, identified by CAS 13139-16-7, is a prominent N-protected amino acid derivative that plays a pivotal role in numerous scientific endeavors. This compound, often referred to as Boc-Ile-OH, is characterized by its isoleucine core protected by a tert-butyloxycarbonyl (Boc) group, rendering it a stable and versatile building block for complex organic synthesis.
The physical properties of Boc-L-Isoleucine are critical for its effective use. Typically appearing as a white crystalline powder, it possesses a melting point in the range of 66-69 °C. Its molecular formula is C11H21NO4, with a molecular weight of approximately 231.29 g/mol. These characteristics, combined with its high purity (often stated as ≥99%), ensure predictable behavior in reaction conditions. Researchers often source this material from manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., to guarantee consistent quality for their experiments.
The applications of Boc-L-Isoleucine are widespread, primarily centering around its use in peptide synthesis. As a core component in Boc Solid-Phase Peptide Synthesis (SPPS), it allows for the controlled addition of isoleucine residues into peptide chains. This is fundamental for creating synthetic peptides that mimic natural proteins or possess novel therapeutic activities. Its utility also extends to analytical chemistry, where it can be used as a standard for quantifying amino acid content in biological samples, thereby aiding in the study of metabolic pathways.
In addition to peptide synthesis and analytical applications, Boc-L-Isoleucine is a valuable tool in biotechnology for protein modification studies and in medicinal chemistry for designing enzyme inhibitors and other drug candidates. Its specific role in research highlights the importance of having access to high-quality, well-characterized chemical compounds. When professionals need to buy Boc-L-Isoleucine for their critical research, they rely on the availability of such intermediates from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD., ensuring that scientific progress is not hindered by reagent quality.
The physical properties of Boc-L-Isoleucine are critical for its effective use. Typically appearing as a white crystalline powder, it possesses a melting point in the range of 66-69 °C. Its molecular formula is C11H21NO4, with a molecular weight of approximately 231.29 g/mol. These characteristics, combined with its high purity (often stated as ≥99%), ensure predictable behavior in reaction conditions. Researchers often source this material from manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., to guarantee consistent quality for their experiments.
The applications of Boc-L-Isoleucine are widespread, primarily centering around its use in peptide synthesis. As a core component in Boc Solid-Phase Peptide Synthesis (SPPS), it allows for the controlled addition of isoleucine residues into peptide chains. This is fundamental for creating synthetic peptides that mimic natural proteins or possess novel therapeutic activities. Its utility also extends to analytical chemistry, where it can be used as a standard for quantifying amino acid content in biological samples, thereby aiding in the study of metabolic pathways.
In addition to peptide synthesis and analytical applications, Boc-L-Isoleucine is a valuable tool in biotechnology for protein modification studies and in medicinal chemistry for designing enzyme inhibitors and other drug candidates. Its specific role in research highlights the importance of having access to high-quality, well-characterized chemical compounds. When professionals need to buy Boc-L-Isoleucine for their critical research, they rely on the availability of such intermediates from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD., ensuring that scientific progress is not hindered by reagent quality.
Perspectives & Insights
Molecule Vision 7
“This is fundamental for creating synthetic peptides that mimic natural proteins or possess novel therapeutic activities.”
Alpha Origin 24
“Its utility also extends to analytical chemistry, where it can be used as a standard for quantifying amino acid content in biological samples, thereby aiding in the study of metabolic pathways.”
Future Analyst X
“In addition to peptide synthesis and analytical applications, Boc-L-Isoleucine is a valuable tool in biotechnology for protein modification studies and in medicinal chemistry for designing enzyme inhibitors and other drug candidates.”