For professionals in chemical synthesis and pharmaceutical research, understanding the nuances of key reagents is crucial for project success. Boc-Met-OH, or N-Boc-L-methionine, is one such indispensable compound. Its role as a protected amino acid derivative makes it a cornerstone in various synthetic pathways, particularly in peptide chemistry.

Chemically, Boc-Met-OH is characterized by the presence of a tert-butyloxycarbonyl (Boc) group attached to the amino nitrogen of L-methionine. This protection strategy is widely employed in organic synthesis, especially in solid-phase peptide synthesis (SPPS), to control the reactivity of the amino group. Methionine, identified by its sulfur-containing side chain, is an essential amino acid with unique chemical properties that can influence peptide structure and function. The Boc protection allows for the stepwise assembly of peptide chains, ensuring that reactions occur at specific sites, thereby minimizing unwanted side products and improving yield and purity.

Key technical specifications for Boc-Met-OH include its CAS number 2488-15-5, and its molecular formula C10H19NO4S, with a molecular weight of approximately 249.3 g/mol. It is often described as a light yellow viscous liquid or crystalline solid, with a melting point typically in the range of 47-50°C. While generally stable, it is noted that it can form an oil that can be reverted to a solid state under specific conditions, a detail useful for researchers when handling the material. Understanding these physical and chemical properties is vital for proper storage and application.

The production of Boc-Met-OH involves the esterification of the carboxyl group of methionine and subsequent protection of the amino group with the Boc moiety. Manufacturers adhere to strict quality control measures to ensure high purity, as even minor impurities can significantly impact the outcomes of sensitive synthesis processes. When researchers look to buy Boc-Met-OH, they are often seeking a reliable supply chain from manufacturers who can guarantee batch-to-batch consistency and purity levels that meet stringent research standards.

For procurement specialists, identifying a reputable manufacturer and supplier is a critical step. Suppliers in China are recognized for their significant contributions to the global fine chemical market, offering Boc-Met-OH at competitive prices. When evaluating a supplier, it is beneficial to inquire about their production capabilities, quality assurance protocols, and willingness to provide technical support. The price of Boc-Met-OH is a consideration, but the true value lies in its consistent quality and the reliability of its supply, especially for researchers working on demanding projects or scaling up for pharmaceutical applications.

In conclusion, Boc-Met-OH is a fundamental reagent for anyone involved in peptide synthesis or related organic chemistry. By understanding its properties, production, and the importance of sourcing from quality-assured manufacturers, researchers can confidently procure this essential amino acid derivative to advance their scientific endeavors.