For chemists engaged in organic synthesis and medicinal chemistry, having a robust toolkit of building blocks is essential for innovation. Boc-Phg-OH (N-tert-butoxycarbonyl-L-phenylglycine) is one such versatile compound, widely employed in peptide synthesis and as a key intermediate in the preparation of various complex organic molecules. This article provides chemists with a closer look at the properties and applications of Boc-Phg-OH, emphasizing the importance of sourcing from reliable manufacturers.

Chemically, Boc-Phg-OH is characterized by the presence of a chiral alpha-carbon, an aromatic phenyl group, and the tert-butoxycarbonyl (Boc) protecting group on the amine. The Boc group is crucial for its utility in synthesis, as it can be selectively removed under mild acidic conditions, allowing for controlled peptide bond formation or further functionalization at the amino terminus. Its molecular weight and typical melting point (around 88-91°C) are important parameters for handling and reaction design. When chemists decide to buy Boc-Phg-OH, these properties inform their experimental planning.

The primary application of Boc-Phg-OH is in solid-phase peptide synthesis (SPPS), where it is coupled to a growing peptide chain attached to a solid resin. The L-enantiomer is particularly important for producing biologically active peptides. Beyond peptides, Boc-Phg-OH serves as a chiral building block for synthesizing heterocyclic compounds, amino alcohol derivatives, and other complex structures relevant to medicinal chemistry. The ability to modify either the carboxyl group or, after deprotection, the amino group, adds to its synthetic flexibility.

Procuring Boc-Phg-OH requires careful consideration of its source. A reputable manufacturer will offer detailed specifications, including purity assays (e.g., by HPLC) and optical rotation data to confirm enantiomeric purity. Understanding the Boc-Phg-OH price in relation to purity and quantity is also vital for budget management in R&D projects. Chemists often prefer suppliers who provide readily available technical support and transparent documentation, facilitating smoother project execution.

In conclusion, Boc-Phg-OH is a highly valuable intermediate for synthetic chemists. Its unique structure and the protective nature of the Boc group make it indispensable for both peptide synthesis and broader organic chemistry applications. We, as a leading Boc-Phg-OH manufacturer, are committed to providing chemists with the high-quality materials they need to drive their research forward. We invite you to purchase Boc-Phg-OH from our extensive catalog and experience our commitment to excellence.