In the dynamic pharmaceutical industry, a deep understanding of chemical intermediates is vital for successful product development. BOC-Pyr-Oet, known by its CAS number 144978-12-1, is a significant pharmaceutical intermediate that warrants close examination. This article provides an overview of its properties, its essential uses in drug synthesis, and guidance on sourcing this compound effectively.

BOC-Pyr-Oet, chemically recognized as Boc-L-pyroglutamic acid ethyl ester, is an organic compound derived from pyroglutamic acid. Its molecular formula is C12H19NO5, and it possesses a molecular weight of 257.28. Typically presenting as a white solid, its melting point is consistently reported in the range of 52.0 to 56.0 °C. The presence of the tert-butyloxycarbonyl (Boc) protecting group is key to its utility in multi-step organic synthesis, allowing for controlled reactions and the creation of complex molecular architectures.

The applications of BOC-Pyr-Oet are primarily centered around its role as a building block for various pharmaceutical compounds. It is a crucial intermediate in the synthesis of therapeutic agents designed to combat significant diseases. Specifically, it is utilized in the manufacturing process of Hepatitis C enzyme inhibitors and alkyl renin inhibitors. These applications highlight its importance in developing treatments for conditions that affect millions worldwide, underscoring the need for a reliable supply chain.

For procurement professionals and R&D scientists, the sourcing of BOC-Pyr-Oet requires careful consideration. When you seek to purchase this intermediate, it is beneficial to explore global manufacturers, with China being a prominent source for high-quality chemical intermediates. Reputable suppliers offer BOC-Pyr-Oet with high purity (often 99%+) and provide comprehensive documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS). Prioritizing manufacturers who can offer competitive pricing and consistent availability is essential for managing project budgets and timelines.

Furthermore, establishing a relationship with a trusted supplier ensures that you receive a product that meets pharmacopoeial standards if required, and that is packaged appropriately for safe handling and storage. Understanding the manufacturer's production capacity and their ability to scale up production is also important for long-term projects. By diligently vetting potential suppliers and understanding the technical specifications of BOC-Pyr-Oet, pharmaceutical companies can secure a dependable source for this indispensable intermediate, thereby facilitating efficient and successful drug development.