In the realm of advanced chemical synthesis and life sciences research, specialized building blocks are indispensable for creating novel molecules with tailored properties. Boc-(S)-3-Amino-5-hexynoic acid is one such critical intermediate, valued for its unique combination of a protected amino group and a terminal alkyne. As a leading manufacturer and supplier, we aim to provide a clear understanding of this compound's characteristics and its broad applicability.

Boc-(S)-3-Amino-5-hexynoic acid, identified by its CAS number 270596-47-9, is a chiral, non-canonical amino acid derivative. Its structure features a six-carbon chain with a terminal alkyne at position 5 and an amino group at position 3, which is protected by a tert-butyloxycarbonyl (Boc) group. The 'S' designation refers to its specific stereochemical configuration at the chiral center, which is crucial for biological interactions and stereoselective synthesis. The Boc group offers robust protection during various chemical reactions and can be readily removed under mild acidic conditions, revealing a primary amine for subsequent functionalization.

The terminal alkyne group is the key to many of its advanced applications. This functional group is highly amenable to 'click chemistry' reactions, most notably the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). This bioorthogonal reaction allows for the efficient and specific formation of triazole rings, enabling the conjugation of this amino acid derivative to a wide array of other molecules. This makes it an ideal building block for creating unnatural peptides, peptide-drug conjugates, fluorescent probes, and various research tools in chemical biology.

For researchers and procurement professionals looking to buy Boc-(S)-3-Amino-5-hexynoic acid, understanding its purity and the reliability of its supply is vital. Our company, as a dedicated manufacturer and supplier in China, ensures that we deliver high-purity material with excellent enantiomeric excess. This commitment to quality is essential for achieving reproducible results in sensitive applications like peptide synthesis or advanced chemical labeling. We offer competitive pricing and can accommodate bulk purchase requirements, making us a valuable partner for your R&D needs.

The synthesis of Boc-(S)-3-Amino-5-hexynoic acid typically involves multi-step organic chemistry processes, carefully controlled to maintain stereochemical integrity. Its stability under various conditions, particularly its inertness to basic reagents while being sensitive to acidic deprotection, dictates its optimal use in synthetic strategies. When considering your next project that requires advanced amino acid building blocks, we encourage you to request a quote for Boc-(S)-3-Amino-5-hexynoic acid. We are confident in our ability to supply you with a product that meets your stringent quality demands.