N-tert-Butoxycarbonyl-O-benzyl-L-serine (Boc-Ser(Bzl)-OH), identified by its CAS number 23680-31-1, is a vital compound in modern organic and medicinal chemistry. As a leading producer of fine chemicals, we provide detailed insights into its synthesis, crucial properties, and broad applications, particularly for researchers and formulators looking to buy high-quality materials.

Synthesis and Purity: The preparation of Boc-Ser(Bzl)-OH involves sophisticated chemical transformations. A common and efficient method is the cesium carbonate-mediated benzylation of N-Boc-L-serine. This process leverages the reactivity of the hydroxyl group on serine while the amine and carboxyl groups are protected. The resulting product typically boasts high purity (≥99%), a critical factor for its use as a pharmaceutical intermediate. We pride ourselves on being a consistent manufacturer of this compound, ensuring that each batch meets rigorous quality standards.

Key Properties: Boc-Ser(Bzl)-OH is characterized by its specific physical and chemical attributes. It typically appears as a white powder. The presence of the Boc group allows for acid-labile deprotection, a technique widely employed in peptide synthesis. The benzyl group on the hydroxyl moiety offers orthogonal protection, meaning it can be removed independently under different conditions, often via hydrogenolysis. These properties make it a versatile building block.

Applications in Peptide Synthesis: The primary application for Boc-Ser(Bzl)-OH lies in peptide synthesis. It serves as a protected serine residue that can be strategically incorporated into peptide chains. This is essential for creating peptides with specific sequences and functionalities for therapeutic drugs, diagnostic agents, and biochemical research tools. Researchers often seek to purchase this compound to ensure the integrity and specific targeting of their synthesized peptides.

Broader R&D Use: Beyond peptide synthesis, Boc-Ser(Bzl)-OH functions as a chiral building block in various organic synthesis endeavors. Its well-defined stereochemistry and reactive functionalities make it valuable for constructing complex chiral molecules. For those seeking a reliable supplier of CAS 23680-31-1, partnering with an established manufacturer in China guarantees quality and competitive price. We are dedicated to supporting your research and development projects with our premium chemical offerings.