For professionals in the chemical synthesis, pharmaceutical research, and agrochemical development sectors, understanding the precise properties and applications of key intermediates is vital. This article focuses on 5-Bromo-1,3-dichloro-2-fluorobenzene, identified by its unique CAS number 17318-08-0, providing a comprehensive overview of its characteristics and utility.

Chemical Identity and Properties of CAS 17318-08-0

5-Bromo-1,3-dichloro-2-fluorobenzene is a halogenated aromatic compound with the molecular formula C6H2BrCl2F. Its molecular weight is approximately 243.88 g/mol. As indicated by its typical specifications, this compound is usually found as a yellowish liquid. Key physical properties often cited include a boiling point of around 234°C and a density of approximately 1.823 g/cm³. It is crucial for users to note its flash point, typically around 96°C, which signifies its flammability and the need for appropriate handling procedures.

The purity of CAS 17318-08-0 is a critical factor for its effective use. Manufacturers commonly guarantee an assay of ≥98.5%, ensuring that the intermediate is suitable for sensitive chemical reactions where impurities could lead to unwanted side products or reduced yields. For those looking to buy 5-Bromo-1,3-dichloro-2-fluorobenzene, confirming this purity level is a standard procurement step.

Applications in Synthesis: A Versatile Intermediate

The primary utility of 5-Bromo-1,3-dichloro-2-fluorobenzene lies in its role as a versatile intermediate in organic synthesis. Its structure, featuring multiple halogen atoms, makes it an excellent building block for creating more complex molecules:

  • Pharmaceutical Synthesis: It serves as a key intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). The bromine atom allows for facile derivatization through various coupling reactions, enabling the construction of diverse heterocyclic and aromatic systems common in drug molecules.
  • Agrochemical Development: This compound is also instrumental in the development of new pesticides, herbicides, and fungicides. Its halogenation pattern can contribute to the biological activity and environmental stability of these crop protection agents.
  • Research and Development: In academic and industrial research labs, CAS 17318-08-0 is utilized for exploring novel synthetic pathways and developing new chemical entities.

Sourcing Considerations

When sourcing 5-Bromo-1,3-dichloro-2-fluorobenzene, procurement managers and research scientists should seek out reliable manufacturers and suppliers. Companies offering this intermediate often provide detailed technical data sheets and are prepared to offer competitive quotes. The availability of this compound from a trusted manufacturer in China can ensure both quality and cost-effectiveness for your projects.

Understanding the chemical properties and application scope of CAS 17318-08-0 is fundamental for its efficient and safe utilization. Its role as a versatile intermediate underscores its importance in advancing fields like medicine and agriculture.