For chemists and material scientists engaged in advanced synthesis, understanding the properties and applications of specific chemical compounds is crucial. Among the vast array of specialized chemicals, organosilicon compounds play an increasingly important role, particularly in the pharmaceutical and materials science sectors. One such compound, identified by CAS number 17477-97-3, is 3-Trisiloxanol, 1,1,1,5,5,5-hexamethyl-3-[(trimethylsilyl)oxy]-. This article explores its characteristics and significance as a chemical intermediate.

What is CAS 17477-97-3?

3-Trisiloxanol, 1,1,1,5,5,5-hexamethyl-3-[(trimethylsilyl)oxy]- is an organosilicon compound with the molecular formula C9H28O4Si4. Its structure features a trisiloxane backbone with hexamethyl substitution and a trimethylsilyl ether functional group. It is typically supplied as a white powder, indicating a solid state at room temperature. The high purity, often exceeding 99%, makes it suitable for demanding applications where precise chemical reactions are required.

Properties and Chemical Significance:

  • Organosilicon Nature: As an organosilicon compound, it benefits from the unique chemistry of silicon-oxygen and silicon-carbon bonds, offering different reactivity and stability profiles compared to purely organic molecules.
  • Trimethylsilyl Ether: The presence of the trimethylsilyl ether group (-(trimethylsilyl)oxy-) is significant. This functional group can act as a protecting group or can be selectively cleaved under specific conditions, allowing for controlled chemical transformations.
  • Trisiloxane Backbone: The trisiloxane structure provides a stable silicon-oxygen framework, which can be incorporated into larger molecules to impart specific properties.
  • High Purity: For chemical synthesis, especially in pharmaceutical applications, maintaining high purity is critical. Suppliers ensure that CAS 17477-97-3 is provided with minimal impurities, facilitating reproducible and efficient reaction outcomes.

Applications as a Chemical Intermediate:

The primary utility of 3-Trisiloxanol, 1,1,1,5,5,5-hexamethyl-3-[(trimethylsilyl)oxy]- lies in its role as a chemical intermediate. Its specific structure and reactive functional groups make it valuable in several areas:

  • Pharmaceutical Synthesis: It serves as a building block or reagent in the synthesis of Active Pharmaceutical Ingredients (APIs). The organosilicon moiety can be incorporated into drug molecules to modify pharmacokinetic properties or to act as a linker.
  • Specialty Chemicals: Beyond pharmaceuticals, this compound can be used in the development of specialty chemicals, advanced materials, or research reagents where its unique silicon-based structure is advantageous.
  • Research and Development: R&D chemists utilize such intermediates to explore new synthetic routes, develop novel compounds, and investigate the properties of organosilicon-containing molecules.

Sourcing High-Quality Intermediates:

When seeking to buy chemicals like CAS 17477-97-3, it is essential to partner with reputable manufacturers and suppliers. A reliable supplier will not only offer a product with confirmed specifications (like ≥99% purity) but also provide comprehensive documentation and support. For those looking to procure this organosilicon intermediate, especially from China, understanding the supplier's commitment to quality and manufacturing standards is key to ensuring successful project outcomes.

In summary, 3-Trisiloxanol, 1,1,1,5,5,5-hexamethyl-3-[(trimethylsilyl)oxy]- (CAS 17477-97-3) is a significant organosilicon intermediate with diverse potential in chemical synthesis, particularly within the pharmaceutical industry. Its specific structure and high purity make it a valuable component for advanced chemical research and production.