For professionals in the chemical, pharmaceutical, and agrochemical industries, understanding the specifics of key chemical intermediates is essential for successful research and development. This article focuses on 2,3-Diaminofluorobenzene, identified by its CAS number 18645-88-0. We will explore its fundamental properties, common applications, and the critical importance of sourcing it from reliable manufacturers and suppliers.

What is 2,3-Diaminofluorobenzene (CAS 18645-88-0)?

2,3-Diaminofluorobenzene is an organic compound characterized by a benzene ring substituted with two amine groups and one fluorine atom. Its molecular formula is C6H7FN2, and its molecular weight is approximately 126.13 g/mol. This compound typically appears as a solid at room temperature, with reported melting points generally falling in the range of 34-43°C or 40.9-42.2°C. High purity grades, commonly 98% or higher, are available from specialized chemical suppliers, ensuring its suitability for demanding synthetic applications.

Key Chemical Properties and Specifications

Understanding the properties of 2,3-Diaminofluorobenzene is crucial for its effective use in synthesis. Key specifications often include:

  • CAS Number: 18645-88-0
  • Molecular Formula: C6H7FN2
  • Molecular Weight: 126.13 g/mol
  • Appearance: Solid
  • Melting Point: 34-43°C (or 40.9-42.2°C)
  • Purity: Typically 98% (GC)

These specifications, particularly purity, are vital for reproducible results in complex organic synthesis. When you look to buy this chemical, always verify these details with your supplier.

Applications in Synthesis

The primary utility of 2,3-Diaminofluorobenzene lies in its role as a versatile building block in organic synthesis. It is widely employed in:

  • Pharmaceutical Intermediate Synthesis: It is a key precursor for the synthesis of benzimidazole and benzoxazole derivatives, which are core structures in many pharmaceutical agents, including inhibitors of Rho kinase.
  • Agrochemical Development: Used in the creation of advanced agrochemical products.
  • Material Science: Explored for its potential in developing novel functional materials.

Its specific arrangement of functional groups makes it highly reactive and adaptable for various cyclization and derivatization reactions.

Sourcing from Reliable Manufacturers and Suppliers

Securing a consistent supply of high-quality 2,3-Diaminofluorobenzene is essential for research and production continuity. As a leading manufacturer and supplier in China, we specialize in providing this compound with guaranteed purity and detailed technical documentation, including COAs. We understand the needs of researchers and industrial clients, offering competitive pricing and reliable logistics. When you need to buy CAS 18645-88-0, partnering with a trusted source like us ensures that your projects are supported by quality chemical intermediates.

In conclusion, 2,3-Diaminofluorobenzene (CAS 18645-88-0) is a significant organic intermediate with diverse applications. Its chemical properties, particularly its purity and reactivity, make it indispensable in modern synthetic chemistry. By focusing on reliable sourcing from experienced manufacturers, you can ensure the success of your research and production endeavors.