In the intricate world of pharmaceutical manufacturing and research, chemical intermediates serve as the foundational building blocks for life-saving medications. Among these essential compounds is (R)-(+)-alpha-[(3-Methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-acetic acid sodium salt, identified by its CAS number 26774-89-0. This article aims to provide a comprehensive understanding of this compound, its significance, and how B2B buyers can effectively procure it from reliable suppliers.

What is CAS 26774-89-0?

CAS 26774-89-0 is a complex organic molecule belonging to the class of amino acid derivatives. Its chemical name, (R)-(+)-alpha-[(3-Methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-acetic acid sodium salt, hints at its sophisticated structure, including a cyclohexadiene ring, an amino group, and ester functionalities, rendered as a sodium salt for improved solubility and stability. It is characterized by its white to off-white powder appearance and a melting point of approximately 240°C with decomposition.

The Significance in Pharmaceutical Synthesis

The primary application of CAS 26774-89-0 lies in its role as a critical intermediate for the synthesis of pharmaceuticals, most notably antibiotics. It is a key precursor in the production of Cephradine, a broad-spectrum antibiotic used to treat various bacterial infections. The specific chiral nature of this intermediate is vital for the bioactivity of the final drug. Pharmaceutical R&D scientists and production managers frequently seek this compound when developing or manufacturing drugs that require its unique structural features.

Procurement Considerations for B2B Buyers

When you plan to buy CAS 26774-89-0, several factors are crucial for successful sourcing. As a procurement professional, you'll be looking for manufacturers and suppliers who can consistently provide this intermediate with high purity (typically 98% or above). It is essential to obtain a detailed Certificate of Analysis (CoA) with each batch to verify its specifications and compliance.

Consider the following when sourcing:

  • Supplier Reputation: Look for suppliers with a strong track record in the fine chemical and pharmaceutical intermediate market. Companies from China are often competitive in both price and quality.
  • Supply Capacity: Ensure the supplier can meet your projected order volumes, from laboratory-scale R&D quantities to commercial production batches.
  • Pricing and Payment Terms: Compare quotes from multiple suppliers to secure competitive pricing. Understanding payment terms (e.g., L/C, T/T) and incoterms (e.g., FOB, CIF) is also vital for cost management.
  • Technical Support: A supplier that offers technical assistance can be invaluable, especially when integrating a new intermediate into a complex synthesis process.

Where to Find Reliable Suppliers

The global market offers numerous suppliers for CAS 26774-89-0. For instance, manufacturers and distributors in China are well-positioned to supply this product efficiently. When searching for a supplier, utilize keywords like 'buy CAS 26774-89-0,' 'pharmaceutical intermediate supplier China,' or '26774-89-0 manufacturer price' to find relevant sources. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are examples of reliable partners in this sector.

In conclusion, CAS 26774-89-0 is an indispensable chemical intermediate for the pharmaceutical industry. By understanding its properties, applications, and procurement best practices, B2B buyers can ensure they source this vital compound effectively, driving innovation and success in their drug development and manufacturing endeavors.