For professionals in the pharmaceutical and chemical industries, CAS numbers are vital identifiers for specific chemical compounds. CAS 268557-49-9 refers to Diethyl 2-Acetamido-2-[2-(4-octylphenyl)-2-oxo-ethyl]malonate, a crucial intermediate in the synthesis of Fingolimod hydrochloride, a significant pharmaceutical agent. Understanding the sourcing, applications, and supply chain for this specific compound is essential for researchers and procurement specialists.

What is CAS 268557-49-9?
This compound, also known by synonyms such as Diethyl 2-Acetamido-2-[2-(4-octylphenyl)-2-oxo-ethyl]malonate, plays a pivotal role in the production pathway of Fingolimod. Fingolimod is used in the treatment of multiple sclerosis, making its intermediates highly sought after by pharmaceutical manufacturers. The chemical structure, with its specific malonate ester and octylphenyl functionalities, is precisely designed for subsequent reactions in the API synthesis.

Sourcing Strategies and Manufacturer Insights
When looking to buy CAS 268557-49-9, it is imperative to partner with reliable manufacturers and suppliers. Global sourcing from reputable companies, particularly those based in regions with strong chemical manufacturing capabilities like China, can offer competitive pricing and consistent quality. Key considerations for buyers include the purity level (often specified as ≥95.0%), the physical form (typically a powder), and the packaging options available (e.g., 25 kg drums). Obtaining a formal quote from potential suppliers is a standard practice to evaluate pricing and terms.

Applications and Research Relevance
The primary application of Diethyl 2-Acetamido-2-[2-(4-octylphenyl)-2-oxo-ethyl]malonate is as a key intermediate in the synthesis of Fingolimod hydrochloride. Its availability is critical for companies involved in generic drug manufacturing and for contract manufacturing organizations (CMOs). Beyond its direct application, this compound can also be of interest in academic research for exploring new synthetic routes or developing related analogs. Understanding the role of this intermediate ensures a more informed procurement process.

Ensuring Quality and Compliance
For any pharmaceutical intermediate, quality assurance is non-negotiable. Manufacturers should provide comprehensive documentation, including Certificates of Analysis (CoA), detailing specifications such as assay, moisture content, and impurity profiles. Adherence to Good Manufacturing Practices (GMP) or similar quality standards is a significant advantage when selecting a supplier. By focusing on these aspects, pharmaceutical companies can secure a dependable supply of CAS 268557-49-9, thereby supporting the efficient and compliant production of essential medications.