In the precise world of chemical synthesis, accurate identification and reliable sourcing of intermediates are critical for project success. CAS number 496946-78-2 refers to 5-Trifluoromethyl-1H-indole-2-carboxylic acid, a compound that has garnered significant attention for its utility as a building block in various organic synthesis pathways. For researchers and procurement managers alike, understanding this specific intermediate is key to efficient laboratory operations and production planning.

The chemical structure of 5-Trifluoromethyl-1H-indole-2-carboxylic acid combines two important features: the indole heterocyclic ring and a trifluoromethyl substituent. Indoles are prevalent in natural products and pharmaceuticals, often conferring important biological activities. The trifluoromethyl (CF3) group, known for its electron-withdrawing nature and lipophilicity-enhancing properties, can profoundly influence a molecule's reactivity, stability, and interaction with biological targets. This unique combination makes compounds like 5-Trifluoromethyl-1H-indole-2-carboxylic acid exceptionally valuable for medicinal chemistry and the development of new functional materials.

When looking to buy 5-Trifluoromethyl-1H-indole-2-carboxylic acid, the CAS number is the definitive identifier. It ensures that you are procuring the correct chemical entity, free from confusion with similar compounds. Furthermore, a high assay purity, such as the ≥95.0% typically offered, is essential for predictable reaction outcomes in organic synthesis. This level of purity minimizes side reactions and ensures that the desired product is formed efficiently, saving time and resources.

For businesses operating in sectors that rely on this intermediate, such as pharmaceutical manufacturing or specialty chemical production, securing a consistent supply is paramount. Sourcing from a reliable manufacturer and supplier, particularly one based in China, can offer economic advantages and ensure consistent quality. Companies that specialize in providing advanced chemical intermediates understand the importance of rigorous quality control, proper packaging (like 25 kg/drum), and efficient logistics to meet global demand.

In summary, 5-Trifluoromethyl-1H-indole-2-carboxylic acid, identified by CAS 496946-78-2, is a powerful intermediate in the hands of skilled synthetic chemists. Its unique structural attributes and the availability of high-purity material from trusted suppliers make it an indispensable component for innovation in chemical research and industrial applications. Understanding its properties and how to source it effectively is a strategic advantage for any organization engaged in advanced organic synthesis.