For professionals in the chemical and pharmaceutical industries, understanding the nuances of key intermediates is critical for successful synthesis and product development. Methyl 4'-(dibromomethyl)-2-biphenylcarboxylate, identified by its CAS number 1352492-08-0, is one such compound that warrants close examination. Its molecular structure, featuring a biphenyl backbone with specific functional groups, positions it as a valuable building block for a range of complex organic molecules, most notably in pharmaceutical applications.

The compound’s chemical identity is defined by its molecular formula, C15H12Br2O2, and a molecular weight of approximately 384.063. The presence of a dibromomethyl group (-CHBr2) attached to the biphenyl system is a key characteristic, providing reactive sites for further chemical transformations. These bromine atoms are good leaving groups, making the molecule amenable to nucleophilic substitution reactions, which are fundamental in constructing more elaborate molecular structures. The methyl ester group (-COOCH3) also offers potential for hydrolysis or transesterification reactions, adding to its synthetic versatility.

As a pharmaceutical intermediate, Methyl 4'-(dibromomethyl)-2-biphenylcarboxylate is primarily used in the synthesis of APIs. Its role in the production of certain Sartans, a class of drugs used to manage hypertension and cardiovascular diseases, is well-documented. The specific structural features of this intermediate are tailored to facilitate the efficient creation of these therapeutic agents. Therefore, for pharmaceutical companies involved in the synthesis of these drugs, sourcing high-purity material is essential. The typical purity requirement of 97% min ensures that the compound will perform reliably in complex, multi-step syntheses, minimizing unwanted side reactions and impurities.

When looking to buy Methyl 4'-(dibromomethyl)-2-biphenylcarboxylate, researchers and purchasing managers often turn to specialized chemical suppliers and manufacturers. The global market for such intermediates is competitive, with many players, including a significant number of reliable producers in China. Engaging with these Chinese manufacturers can provide access to high-quality materials at competitive prices. It is advisable to establish direct communication to understand their production capabilities, quality control measures, and their ability to provide consistent supply for both R&D and larger-scale manufacturing needs.

For those intending to purchase this intermediate, requesting detailed technical specifications and a Certificate of Analysis (CoA) is a standard and necessary step. A free sample can also be invaluable for laboratory evaluation, allowing you to confirm its suitability for your specific synthetic routes and analytical requirements. Understanding the typical storage conditions, such as maintaining an inert atmosphere and cool temperatures (2-8°C), is also important for preserving the compound's integrity.

In conclusion, Methyl 4'-(dibromomethyl)-2-biphenylcarboxylate is a significant intermediate with a defined role in pharmaceutical synthesis. Its chemical properties make it a valuable tool for organic chemists. By partnering with reputable manufacturers, particularly those in China known for their quality and production capacity, businesses can ensure a stable and cost-effective supply of this essential compound, thereby supporting their critical drug development and manufacturing endeavors.