Chemical intermediates are the unsung heroes of the manufacturing world, forming the backbone of complex synthesis processes across various industries, especially pharmaceuticals. Ethyl 4-(1-Methyl-5-nitrobenzimidazol-2-yl)butanoate (CAS: 3543-72-4) exemplifies this critical role. As a key chemical intermediate, its precise specifications and consistent availability directly impact the production of essential medicines.

This compound, often supplied as a white crystalline powder with a purity of ≥99%, features the molecular formula C14H17N3O4 and a molecular weight of 291.30200. These characteristics are vital for its predictable behavior in chemical reactions. Its physical properties, including a density of 1.3 g/cm³, a high boiling point of 481ºC, and a flash point of 244.7ºC, are important data points for process engineers and chemists working with it. The compound is classified as a nitrobenzimidazole derivative, a class of molecules frequently utilized in the synthesis of pharmacologically active substances.

The significance of Ethyl 4-(1-Methyl-5-nitrobenzimidazol-2-yl)butanoate is most pronounced in its application as an intermediate for Bendamustine hydrochloride. Bendamustine is a bifunctional alkylating agent used to treat various hematological cancers, including chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). The synthesis of such a complex and vital drug relies heavily on the purity and structural integrity of its precursors, making this intermediate a critical link in the pharmaceutical supply chain.

For companies seeking to source this chemical intermediate, partnering with a reliable manufacturer and supplier in China, such as NINGBO INNO PHARMCHEM CO.,LTD., is a strategic advantage. Such suppliers offer not only competitive pricing but also a commitment to quality assurance, ensuring that the chemical intermediate meets stringent industry standards. This is crucial for maintaining the integrity of the final pharmaceutical product and for compliance with regulatory requirements.

Proper storage is another key aspect that ensures the longevity and effectiveness of chemical intermediates. Ethyl 4-(1-Methyl-5-nitrobenzimidazol-2-yl)butanoate should be stored in a cool, dry place, in a well-closed container, shielded from moisture and direct light or heat. Adhering to these storage guidelines helps preserve its chemical properties, guaranteeing its suitability for pharmaceutical synthesis.

In conclusion, Ethyl 4-(1-Methyl-5-nitrobenzimidazol-2-yl)butanoate serves as a prime example of an essential chemical intermediate. Its specific properties and applications highlight the importance of meticulous chemical manufacturing and reliable sourcing for the successful production of life-saving medications.