Understanding the Chemical Properties of 2-Bromo-4-fluoroanisole (CAS 452-08-4)
For professionals in the chemical industry, a thorough understanding of a compound's properties is fundamental to its effective and safe utilization. 2-Bromo-4-fluoroanisole, identified by CAS number 452-08-4, is a chemical intermediate whose specific properties dictate its application in various synthetic processes. Sourcing this compound from a reputable manufacturer ensures that these properties are consistently maintained.
The typical appearance of 2-Bromo-4-fluoroanisole is described as a clear liquid, ranging in color from colorless to light orange or yellow. This visual characteristic, along with its density (approximately 1.581 g/mL at 25°C) and refractive index (n20/D 1.545), provides initial indicators of its purity and composition. Its boiling point is noted at around 89 °C at 1 mmHg, suggesting moderate volatility under reduced pressure.
From a safety and handling perspective, 2-Bromo-4-fluoroanisole is classified as an irritant, with risk statements R36/37/38 indicating potential irritation to the eyes, respiratory system, and skin. Therefore, appropriate personal protective equipment (PPE), such as gloves, safety goggles, and lab coats, is essential when handling this chemical. It is advisable to store the compound in a cool, dry place, preferably at 0-8°C, and keep it sealed in a dry environment, away from direct light. This storage protocol helps maintain its stability and prevent degradation.
The molecular formula for 2-Bromo-4-fluoroanisole is C7H6BrFO, with a molecular weight of 205.02. This precise composition is crucial for stoichiometric calculations in chemical reactions. As a key intermediate, its purity, often specified as ≥ 99% by Gas Chromatography (GC), is a critical parameter for users aiming to buy this chemical for precise synthetic applications in pharmaceuticals or agrochemicals.
When procuring 2-Bromo-4-fluoroanisole, it is paramount to partner with reliable manufacturers who provide comprehensive documentation, including detailed Safety Data Sheets (SDS) and Certificates of Analysis (CoA). This ensures that the product meets the expected quality standards and that proper handling procedures are understood, thereby supporting safe and efficient laboratory and industrial operations.
Perspectives & Insights
Quantum Pioneer 24
“Its boiling point is noted at around 89 °C at 1 mmHg, suggesting moderate volatility under reduced pressure.”
Bio Explorer X
“From a safety and handling perspective, 2-Bromo-4-fluoroanisole is classified as an irritant, with risk statements R36/37/38 indicating potential irritation to the eyes, respiratory system, and skin.”
Nano Catalyst AI
“Therefore, appropriate personal protective equipment (PPE), such as gloves, safety goggles, and lab coats, is essential when handling this chemical.”