In the realm of fine chemical synthesis, understanding the intricate properties of intermediates is paramount for successful product development and manufacturing. 3-Isobutylglutaric Acid (CAS: 75143-89-4), a key intermediate in the production of the pharmaceutical Pregabalin, possesses a unique set of chemical and physical characteristics that dictate its utility and handling.

Molecular Structure and Characteristics

The chemical name for 3-Isobutylglutaric Acid is 3-(2-methylpropyl)pentanedioic acid. Its molecular formula is C9H16O4, and it has a molecular weight of approximately 188.22 g/mol. This structure, featuring a glutaric acid backbone with an isobutyl group at the 3-position, is precisely what makes it an effective precursor in the Pregabalin synthesis pathway.

Physical and Chemical Properties: A Deeper Look

The data available for 3-Isobutylglutaric Acid indicates specific properties crucial for industrial application:

  • Appearance: Typically presented as a white to pale brown powder, allowing for easy identification and handling.
  • Purity: High purity, u226599%, is a standard requirement, ensuring minimal impurities that could affect downstream reactions.
  • Moisture Content: A low moisture content (u22640.1%) is critical for stability and to prevent unwanted hydrolysis during storage or processing.
  • Boiling Point: Reported around 326.197 u00b0C at 760 mmHg, indicating its thermal stability under normal processing conditions.
  • Flash Point: A flash point of 165.289 u00b0C suggests it requires elevated temperatures to ignite, offering a reasonable safety margin in manufacturing environments.
  • Density: Approximately 1.126 g/cmu00b3, a standard parameter for chemical handling and volume calculations.

These properties are vital for process chemists and formulators when designing synthesis protocols, selecting appropriate reaction vessels, and ensuring safe storage conditions. For any chemical manufacturer or research scientist aiming to buy 3-Isobutylglutaric Acid, understanding these parameters from a reliable supplier is essential.

Impact on Pregabalin Synthesis

The consistent purity and well-defined chemical properties of 3-Isobutylglutaric Acid directly influence the yield and quality of Pregabalin. Manufacturers who can consistently deliver material meeting these specifications are highly valued in the pharmaceutical supply chain. If you are seeking to purchase this intermediate, verifying these properties with your potential supplier is a critical due diligence step.

By grasping the chemical nuances of 3-Isobutylglutaric Acid, NINGBO INNO PHARMCHEM CO.,LTD. reinforces its position as a knowledgeable and reliable supplier of essential pharmaceutical building blocks. We are committed to providing detailed technical information to support your research and manufacturing needs.