Understanding the Chemical Properties and Applications of D-4-Iodophenylalanine
D-4-Iodophenylalanine (CAS: 62561-75-5) is a fascinating molecule that bridges organic chemistry and the life sciences. As a specialized amino acid derivative, it offers unique chemical properties that make it invaluable for a wide range of research applications. NINGBO INNO PHARMCHEM CO.,LTD. provides this high-purity compound, ensuring researchers have access to reliable chemical building blocks.
Chemically, D-4-Iodophenylalanine is characterized by the presence of an iodine atom substituted at the para position of the phenyl ring, attached to a D-phenylalanine backbone. Its molecular formula is C9H10INO2, with a molecular weight of approximately 291.09 g/mol. The compound typically appears as a white to off-white solid or powder. Its melting point is reported to be around 251 °C, often with decomposition, indicating its stability under moderate conditions but sensitivity to extreme heat.
The reactivity of D-4-Iodophenylalanine stems from both the amino acid functionality and the aryl halide (iodine). The amino and carboxyl groups allow for standard peptide coupling reactions, making it a straightforward incorporation into peptide sequences. The iodine atom, being a good leaving group, makes it amenable to various cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling the synthesis of more complex aryl-substituted molecules.
These chemical characteristics translate into diverse applications. In peptide synthesis, D-4-Iodophenylalanine is used to create modified peptides for SAR studies or to introduce specific spectroscopic probes. Its utility extends to drug discovery, where it can be part of novel therapeutic agents or used as an intermediate in their synthesis. The price of D-4-Iodophenylalanine can vary depending on purity and quantity, reflecting its specialized nature.
Researchers often buy D-4-Iodophenylalanine to explore its potential in areas like protein engineering, where modifications can alter protein function or stability. The ability to perform regioselective reactions at the iodine site offers significant flexibility for chemists. For those seeking a reliable supplier of this essential chemical, NINGBO INNO PHARMCHEM CO.,LTD. offers quality and consistency, ensuring your research projects are well-supported.
Chemically, D-4-Iodophenylalanine is characterized by the presence of an iodine atom substituted at the para position of the phenyl ring, attached to a D-phenylalanine backbone. Its molecular formula is C9H10INO2, with a molecular weight of approximately 291.09 g/mol. The compound typically appears as a white to off-white solid or powder. Its melting point is reported to be around 251 °C, often with decomposition, indicating its stability under moderate conditions but sensitivity to extreme heat.
The reactivity of D-4-Iodophenylalanine stems from both the amino acid functionality and the aryl halide (iodine). The amino and carboxyl groups allow for standard peptide coupling reactions, making it a straightforward incorporation into peptide sequences. The iodine atom, being a good leaving group, makes it amenable to various cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling the synthesis of more complex aryl-substituted molecules.
These chemical characteristics translate into diverse applications. In peptide synthesis, D-4-Iodophenylalanine is used to create modified peptides for SAR studies or to introduce specific spectroscopic probes. Its utility extends to drug discovery, where it can be part of novel therapeutic agents or used as an intermediate in their synthesis. The price of D-4-Iodophenylalanine can vary depending on purity and quantity, reflecting its specialized nature.
Researchers often buy D-4-Iodophenylalanine to explore its potential in areas like protein engineering, where modifications can alter protein function or stability. The ability to perform regioselective reactions at the iodine site offers significant flexibility for chemists. For those seeking a reliable supplier of this essential chemical, NINGBO INNO PHARMCHEM CO.,LTD. offers quality and consistency, ensuring your research projects are well-supported.
Perspectives & Insights
Chem Catalyst Pro
“The iodine atom, being a good leaving group, makes it amenable to various cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling the synthesis of more complex aryl-substituted molecules.”
Agile Thinker 7
“In peptide synthesis, D-4-Iodophenylalanine is used to create modified peptides for SAR studies or to introduce specific spectroscopic probes.”
Logic Spark 24
“Its utility extends to drug discovery, where it can be part of novel therapeutic agents or used as an intermediate in their synthesis.”