For chemists and laboratory technicians working with specialized organic compounds, a thorough understanding of their properties and safe handling procedures is essential. 3-(Difluoromethoxy)bromobenzene (CAS: 262587-05-3) is a fine chemical intermediate frequently encountered in organic synthesis, particularly within the pharmaceutical and agrochemical sectors. Knowing its characteristics ensures efficient and safe utilization.

Key Chemical and Physical Properties:

3-(Difluoromethoxy)bromobenzene is typically described as a yellow liquid. Its key properties, as reported by reputable suppliers and databases, include:

  • Molecular Formula: C7H5BrF2O
  • Molecular Weight: 223.01 g/mol
  • CAS Number: 262587-05-3
  • Appearance: Colorless to light yellow liquid
  • Boiling Point: 196-197 °C (often cited with a note 'lit.', indicating literature value)
  • Density: Approximately 1.585 g/mL at 25 °C
  • Flash Point: Generally above 199 °F (approximately 93 °C), indicating it is combustible but not highly flammable at room temperature.
  • Purity: Commonly available at purities of 97% or higher, essential for precise synthetic work.

Safety and Handling Guidelines:

As an irritant, 3-(Difluoromethoxy)bromobenzene requires careful handling. Standard safety protocols for organic chemicals should always be followed:

  • Personal Protective Equipment (PPE): Wear chemical-resistant gloves, safety goggles with side shields, and appropriate protective clothing to prevent skin and eye contact.
  • Ventilation: Use in a well-ventilated area, preferably under a fume hood, to minimize inhalation of vapors.
  • Storage: Store in a cool, dry, and well-ventilated place, keeping containers tightly sealed. It should be kept away from incompatible materials such as strong oxidizing agents and strong acids.
  • First Aid: In case of contact, rinse immediately with plenty of water. If inhaled, move to fresh air. Seek medical attention if irritation persists or if ingested.

When you are looking to buy 3-(difluoromethoxy)bromobenzene, consulting the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) provided by the manufacturer is crucial. This document offers comprehensive information on hazards, handling, storage, and emergency procedures. A reliable supplier in China will provide all necessary safety documentation alongside the product.

Understanding these chemical properties and adhering to safety guidelines ensures that researchers and industrial chemists can effectively and safely utilize 3-(Difluoromethoxy)bromobenzene in their synthetic endeavors.