For Research and Development scientists in the pharmaceutical and chemical sectors, a deep understanding of a compound's chemical properties is fundamental to its successful application. N-Acetyl-L-cysteine ethyl ester (NACET) is one such compound, garnering attention for its unique chemical structure and resulting therapeutic advantages. As a dedicated supplier and manufacturer of high-purity chemical intermediates, we provide this guide to help R&D professionals effectively utilize NACET. If you are looking to buy N-Acetyl-L-cysteine ethyl ester, understanding its properties is key.

NACET, with the chemical name ethyl (2R)-2-acetamido-3-sulfanylpropanoate and CAS number 59587-09-6, is a derivative of N-acetylcysteine (NAC). Its molecular formula is C7H13NO3S, with a molecular weight of approximately 191.25 g/mol. The key modification from NAC is the esterification of the carboxyl group with an ethyl moiety. This seemingly small change significantly alters its physicochemical properties, most notably its lipophilicity and ability to permeate cell membranes more effectively.

The appearance of NACET is typically a white to off-white crystalline solid. Its melting point is reported around 44.1-44.5 °C. Solubility data indicates good solubility in organic solvents like DMF and DMSO, and moderate solubility in aqueous solutions such as PBS (pH 7.2). This profile allows for flexible formulation strategies, whether for laboratory research or advanced drug delivery systems. For scientists requiring specific solubility data to optimize their research, consulting with a reliable supplier is advisable.

From a reactivity standpoint, NACET retains the crucial sulfhydryl (-SH) group characteristic of cysteine and NAC. This thiol group is responsible for its potent antioxidant activity, allowing it to neutralize reactive oxygen species and participate in redox reactions. The ester linkage, however, can be hydrolyzed in vivo to release NAC and cysteine, providing a sustained delivery of these beneficial molecules. This controlled release mechanism is a significant advantage that drives the demand for NACET. When considering N-Acetyl-L-cysteine ethyl ester price, the advanced chemical engineering behind these properties is a key factor.

In pharmaceutical research and development, NACET serves multiple roles. Its enhanced mucolytic properties make it a prime candidate for respiratory medications. Simultaneously, its robust antioxidant capabilities are valuable for developing therapies against diseases linked to oxidative stress. R&D scientists often use NACET as a model compound for studying cysteine metabolism, glutathione synthesis, and thiol-based drug delivery systems. To ensure the accuracy of experimental results, it is crucial to order N-Acetyl-L-cysteine ethyl ester from a reputable manufacturer with guaranteed purity.

As a leading chemical intermediate supplier, we offer NACET with high purity levels (typically ≥99% via HPLC). Our manufacturing processes are designed to maintain the integrity of the molecule, ensuring it is suitable for sensitive applications such as drug discovery, analytical method development, and quality control. We provide comprehensive documentation, including Certificates of Analysis (CoA), to support your research and regulatory requirements.

In summary, understanding the chemical properties of N-Acetyl-L-cysteine ethyl ester (NACET) is essential for unlocking its full potential in pharmaceutical R&D. Its unique esterified structure, favorable solubility, and dual therapeutic actions as a mucolytic and antioxidant make it a highly sought-after intermediate. We encourage researchers and procurement specialists to partner with us to buy N-Acetyl-L-cysteine ethyl ester and leverage our expertise in chemical synthesis and supply.