For chemists and procurement specialists engaged in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, a thorough understanding of key chemical intermediates is crucial. 2-Fluoro-5-bromoanisole (CAS: 103291-07-2) is one such compound, prized for its unique structural features and versatile reactivity. This article explores its fundamental chemical properties and its significance in various industrial applications.

2-Fluoro-5-bromoanisole is characterized by its physical appearance as a colorless, transparent liquid. This visual cue is important for initial quality assessment. Key physico-chemical properties, such as its boiling point (approximately 205.8 °C at 760 mmHg) and density (around 1.5 g/cm³), provide essential data for process design and handling. The molecular formula C7H6BrFO and molecular weight of 205.024 further define its chemical identity. Importantly, its refractive index is reported as 1.519, a property that can be useful for verification and quality control.

The true value of 2-Fluoro-5-bromoanisole lies in its chemical structure, featuring both a fluorine atom and a bromine atom on an anisole ring. This dual halogenation makes it an exceptionally versatile building block in organic synthesis. The fluorine atom influences the electron density of the aromatic ring and can impart desirable properties like metabolic stability and altered lipophilicity to final products. The bromine atom serves as an excellent leaving group or a handle for palladium-catalyzed cross-coupling reactions, enabling the formation of new carbon-carbon or carbon-heteroatom bonds. This makes it invaluable for constructing complex molecular frameworks commonly found in pharmaceuticals and agrochemicals.

When considering the purchase of 2-Fluoro-5-bromoanisole, it is vital to source from reputable suppliers who can guarantee the specified purity (≥98.0%) and provide accurate technical data. As a trusted supplier, we offer this essential intermediate, understanding the critical role it plays in your research and manufacturing processes. Whether you are looking to buy for laboratory use or for bulk industrial applications, partnering with a reliable manufacturer ensures the quality and consistency needed to drive successful chemical innovation.