For professionals in the chemical and pharmaceutical industries, a thorough understanding of the specifications and properties of key chemical intermediates is fundamental to successful research, development, and manufacturing. 6-Chloroimidazo[1,2-b]pyridazine, identified by its CAS number 6775-78-6, is a compound that warrants detailed attention due to its critical role as a pharmaceutical intermediate, particularly in the synthesis of Cefozopran. This article delves into the essential chemical and physical attributes of this compound.

The compound is chemically classified as 6-Chloroimidazo[1,2-b]pyridazine, with the molecular formula C6H4ClN3 and a corresponding molecular weight of 153.569. Visually, it is described as a white crystal, providing a clear indicator of its physical state and appearance. The density is reported at 1.51g/cm3, a characteristic that can be relevant for formulation and handling procedures. For procurement managers looking to buy this chemical, these basic properties are the starting point for evaluating its suitability for specific applications.

A crucial specification for any pharmaceutical intermediate is its purity. 6-Chloroimidazo[1,2-b]pyridazine is typically supplied with a purity of ≥97.0%. This high level of purity is non-negotiable for applications in drug synthesis, where even minor impurities can have significant downstream effects on reaction yields, product quality, and the safety profile of the final Active Pharmaceutical Ingredient (API). Therefore, when sourcing this compound, verifying the purity through a reliable Certificate of Analysis (CoA) from the manufacturer is a critical step. Suppliers in China, such as ourselves, are dedicated to meeting these stringent purity requirements.

The primary application of 6-Chloroimidazo[1,2-b]pyridazine is as an intermediate in the synthesis of Cefozopran, a broad-spectrum cephalosporin antibiotic. This direct link to a significant pharmaceutical product highlights the demand for this intermediate. Beyond this primary use, its structure as a functionalized heterocycle makes it a versatile building block for researchers in organic chemistry and medicinal chemistry, who may use it for the synthesis of novel compounds with potential biological activities. Obtaining this chemical for research purposes or large-scale manufacturing requires identifying a supplier who can consistently deliver the specified quality.

Understanding the storage requirements is also vital for maintaining the integrity of 6-Chloroimidazo[1,2-b]pyridazine. It is recommended to store it in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances. This ensures the compound's stability over time, preventing degradation and maintaining its specified purity. For companies planning to purchase this intermediate, discussing packaging options, such as the standard 25kg cardboard drum, and storage recommendations with the supplier is a wise practice.

In summary, the detailed specifications of 6-Chloroimidazo[1,2-b]pyridazine, including its appearance, purity, and molecular characteristics, are essential for its effective use in pharmaceutical synthesis and broader chemical research. We encourage potential buyers to engage with us to obtain detailed product information, inquire about pricing for bulk purchases, and ensure a reliable supply of this critical chemical intermediate from a trusted manufacturer.