For organic chemists and researchers working at the forefront of pharmaceutical and material science, a deep understanding of chemical intermediates is fundamental. 6-Methoxynicotinaldehyde (CAS: 65873-72-5) is a compound that warrants close attention due to its versatile reactivity and important applications. This article explores its key chemical properties, common synthesis routes, and the sectors that benefit from its unique characteristics.

Chemically, 6-Methoxynicotinaldehyde is characterized by a pyridine ring substituted with a methoxy group at the 6-position and an aldehyde group at the 3-position. Its molecular formula is C7H7NO2, with a molecular weight of 137.14 g/mol. The compound typically appears as a white to off-white to light yellow crystalline powder, with a melting point between 51-54°C. Its solubility in water is generally low, but it is soluble in common organic solvents, facilitating its use in various reaction media. These properties make it an attractive building block for synthetic chemists aiming to construct more complex molecular structures.

The synthesis of 6-Methoxynicotinaldehyde often involves reactions starting from substituted pyridines. A common preparation method described in chemical literature involves the lithiation of 5-bromo-2-methoxypyridine followed by reaction with N,N-dimethylformamide (DMF). This process, carried out under controlled low temperatures, typically yields the desired aldehyde with good purity, often in the range of 97% or higher. As a manufacturer, optimizing these synthesis pathways to ensure high yield and purity is a primary focus, enabling us to supply reliable material to our clients.

The applications of 6-Methoxynicotinaldehyde are predominantly in two key areas: pharmaceutical synthesis and the development of OLED materials. In pharmaceuticals, it serves as an intermediate for creating compounds with potential therapeutic benefits, often involving complex heterocyclic scaffolds. In the electronics industry, it's used in the synthesis of organic semiconductors for OLED displays, contributing to the development of advanced materials with improved performance characteristics. Researchers looking to buy 6-methoxynicotinaldehyde for these applications value its reactivity and the structural possibilities it unlocks.

For chemical buyers and researchers, identifying a dependable supplier is paramount. As a manufacturer with expertise in fine chemical synthesis, we offer 6-methoxynicotinaldehyde with guaranteed quality and competitive pricing. Whether you are in early-stage research or scaling up production, our team is ready to assist with your requirements. Understanding the chemical nuances of intermediates like 6-methoxynicotinaldehyde empowers your team to drive innovation more effectively.