For chemists, formulators, and procurement specialists, a deep understanding of a chemical compound's specifications is fundamental to its successful application. 3,4-Methylenedioxymandelic Acid (CAS: 27738-46-1) is no exception. This versatile organic intermediate possesses a distinct set of physical and chemical properties that dictate its utility in various industries.

Key Physical Properties

The most common description of 3,4-Methylenedioxymandelic Acid's appearance is a White to Light Brown Solid. This physical state is typical for organic acids of its molecular weight and complexity. Its melting point is consistently reported within the range of 158-162°C. This relatively high melting point indicates a stable solid form at room temperature, which is advantageous for handling, storage, and transportation. The boiling point, often predicted due to its decomposition at higher temperatures, is around 403.5°C at standard atmospheric pressure, further suggesting its robust nature.

Chemical Structure and Reactivity

With the molecular formula C9H8O5, the compound's structure features a mandelic acid backbone substituted with a methylenedioxy group at the 3 and 4 positions of the phenyl ring. This unique combination of functional groups – a carboxylic acid, a hydroxyl group, and the benzodioxole ring – endows it with specific reactivity. The carboxylic acid group allows for salt formation and esterification, while the hydroxyl group can participate in etherification and oxidation reactions. The methylenedioxy moiety is a key structural feature that influences its biological activity and chemical behavior.

Purity and Quality Assurance

When purchasing 3,4-Methylenedioxymandelic Acid, it is crucial to consider its purity. Suppliers typically offer it with a purity of 97% minimum. This level of purity is essential for its applications in pharmaceutical synthesis and as a reference standard, where trace impurities can significantly impact reaction outcomes or analytical results. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. adhere to strict quality control measures to ensure that their products meet these exacting standards.

Other Relevant Specifications

The density of 3,4-Methylenedioxymandelic Acid is approximately 1.553 g/cm³. Information regarding its solubility often notes it is slightly soluble in aqueous bases, DMSO, and methanol. Its stability is characterized as hygroscopic, meaning it can absorb moisture from the air, necessitating appropriate storage conditions (e.g., under an inert atmosphere and refrigeration) to maintain its quality. For procurement managers and R&D chemists, these detailed specifications are vital for ensuring the correct application, handling, and storage of the chemical, thereby guaranteeing successful outcomes in their projects.