Understanding the Chemical Specifications of Ethyl 2-(3-Bromopyridin-2-yl)acetate
For any scientist or procurement manager involved in chemical synthesis, particularly within the pharmaceutical sector, understanding the precise specifications of a chemical compound is paramount. Ethyl 2-(3-Bromopyridin-2-yl)acetate (CAS: 197376-41-3) is a key pharmaceutical intermediate, and its effective utilization hinges on comprehending its detailed chemical profile.
The Significance of Accurate Specifications
When you buy Ethyl 2-(3-Bromopyridin-2-yl)acetate, you're not just buying a name and CAS number; you're investing in a material with specific physical and chemical properties. These specifications dictate its suitability for particular reactions, its stability, and ultimately, the success and purity of the final product. For pharmaceutical applications, adherence to these specifications is critical for regulatory compliance and drug efficacy.
Key Specifications for Ethyl 2-(3-Bromopyridin-2-yl)acetate:
1. Chemical Purity: This is arguably the most critical specification. For pharmaceutical intermediates, high purity is essential to avoid unwanted side reactions and to ensure the final drug product meets stringent quality standards. Typically, Ethyl 2-(3-Bromopyridin-2-yl)acetate is available with a minimum purity of 97%. Higher purities might be available for more demanding applications, and it's always advisable to check the Certificate of Analysis (CoA) provided by the manufacturer.
2. Physical Appearance: The visual state of the chemical can offer initial clues about its quality. Ethyl 2-(3-Bromopyridin-2-yl)acetate is generally described as a light yellow liquid. Any significant deviation from this appearance might indicate degradation or contamination, warranting further investigation.
3. Molecular Formula and Weight: The molecular formula, C9H10BrNO2, and molecular weight, approximately 244.09 g/mol, are fundamental identifiers. These are crucial for stoichiometric calculations in synthesis and for analytical identification.
4. Boiling Point and Flash Point: The boiling point (around 278℃) provides insight into its volatility, which is important for distillation and purification processes. The flash point (around 122℃) indicates its flammability, essential for safe handling and storage protocols.
5. Density: With a density of approximately 1.451, this parameter is useful for volume-to-mass conversions in practical laboratory work.
6. Storage Conditions: Proper storage is key to maintaining purity and stability. This compound is typically stored sealed in dry conditions at room temperature, away from incompatible materials and ignition sources. Understanding these requirements from the supplier is vital for end-users.
Why These Specifications Matter to You:
As an R&D scientist, precise specifications mean you can rely on predictable reaction outcomes. As a procurement manager, they enable you to compare offerings from different manufacturers effectively and ensure you are meeting the quality requirements for your downstream processes. When you source Ethyl 2-(3-Bromopyridin-2-yl)acetate, always ask for the CoA and verify that it aligns with your project's needs.
Partnering with reputable suppliers, such as dedicated chemical manufacturers in China, who provide accurate and detailed specifications is fundamental to successful procurement. They understand the importance of quality and can be a reliable source for this critical pharmaceutical intermediate. When you need to buy this compound, remember that the details in its specification sheet are your roadmap to successful synthesis and application.
Perspectives & Insights
Logic Thinker AI
“When you source Ethyl 2-(3-Bromopyridin-2-yl)acetate, always ask for the CoA and verify that it aligns with your project's needs.”
Molecule Spark 2025
“Partnering with reputable suppliers, such as dedicated chemical manufacturers in China, who provide accurate and detailed specifications is fundamental to successful procurement.”
Alpha Pioneer 01
“They understand the importance of quality and can be a reliable source for this critical pharmaceutical intermediate.”