Understanding the Chemical Synthesis and Properties of 3-Hydroxy-2-methyl-4-quinolinecarboxylic Acid
For chemists and researchers, a deep understanding of a compound's synthesis and inherent properties is fundamental to its effective utilization. 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid (CAS 117-57-7) is no exception. This heterocycle is synthesized through specific chemical reactions, and its distinct properties dictate its wide-ranging applications, particularly as a key intermediate in various chemical sectors.
The synthesis of 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid typically involves reactions starting from readily available precursors. One common method described in literature involves the action of halo acetone on salts of isatin acids in the presence of alkaline earth hydroxides. These methods are optimized to yield the compound with high purity, which is crucial for its subsequent use in demanding applications like pharmaceutical synthesis.
The physical and chemical properties of 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid are noteworthy. It typically appears as a yellow to green powder. Key properties include a melting point of around 235 °C (with decomposition), a moderate solubility in water (0.04 g/L at 20 °C), and specific reactivity due to its hydroxyl, methyl, and carboxylic acid groups attached to the quinoline ring.
These properties render it highly valuable as a chemical intermediate. Its ability to undergo further chemical transformations, such as acylation, alkylation, and condensation, makes it a versatile building block. This reactivity is precisely what makes it sought after in the pharmaceutical industry for synthesizing active pharmaceutical ingredients (APIs), in the dye industry for creating specific colorants, and in material science for developing functional organic materials.
For companies looking to purchase or source 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid, understanding these synthesis routes and properties is paramount. Manufacturers like NINGBO INNO PHARMCHEM CO., LTD. invest in robust synthesis processes to ensure consistent quality and supply. The price of this intermediate is influenced by the complexity of its synthesis, purity levels, and market demand, reflecting its importance in high-value chemical production.
In essence, 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid is a testament to the power of organic synthesis, providing a foundational molecule that enables innovation across multiple scientific and industrial frontiers.
The synthesis of 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid typically involves reactions starting from readily available precursors. One common method described in literature involves the action of halo acetone on salts of isatin acids in the presence of alkaline earth hydroxides. These methods are optimized to yield the compound with high purity, which is crucial for its subsequent use in demanding applications like pharmaceutical synthesis.
The physical and chemical properties of 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid are noteworthy. It typically appears as a yellow to green powder. Key properties include a melting point of around 235 °C (with decomposition), a moderate solubility in water (0.04 g/L at 20 °C), and specific reactivity due to its hydroxyl, methyl, and carboxylic acid groups attached to the quinoline ring.
These properties render it highly valuable as a chemical intermediate. Its ability to undergo further chemical transformations, such as acylation, alkylation, and condensation, makes it a versatile building block. This reactivity is precisely what makes it sought after in the pharmaceutical industry for synthesizing active pharmaceutical ingredients (APIs), in the dye industry for creating specific colorants, and in material science for developing functional organic materials.
For companies looking to purchase or source 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid, understanding these synthesis routes and properties is paramount. Manufacturers like NINGBO INNO PHARMCHEM CO., LTD. invest in robust synthesis processes to ensure consistent quality and supply. The price of this intermediate is influenced by the complexity of its synthesis, purity levels, and market demand, reflecting its importance in high-value chemical production.
In essence, 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid is a testament to the power of organic synthesis, providing a foundational molecule that enables innovation across multiple scientific and industrial frontiers.
Perspectives & Insights
Future Origin 2025
“For companies looking to purchase or source 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid, understanding these synthesis routes and properties is paramount.”
Core Analyst 01
“The price of this intermediate is influenced by the complexity of its synthesis, purity levels, and market demand, reflecting its importance in high-value chemical production.”
Silicon Seeker One
“In essence, 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid is a testament to the power of organic synthesis, providing a foundational molecule that enables innovation across multiple scientific and industrial frontiers.”