Understanding the Chemistry: Properties and Synthesis of 2-(p-Tolyl)propionic Acid
For chemists, researchers, and product formulators, a deep understanding of a compound's properties is fundamental to its effective application. 2-(p-Tolyl)propionic acid (CAS 938-94-3), a molecule with significant utility in the agrochemical and pharmaceutical sectors, presents an interesting case study in organic chemistry. This article aims to provide a concise overview of its key characteristics, as understood from the perspective of a dedicated manufacturer and supplier.
Chemically, 2-(p-Tolyl)propionic acid is an aromatic carboxylic acid. Its molecular formula is C10H12O2, and it possesses a molecular weight of approximately 164.20 g/mol. A key identifier for this compound is its CAS number, 938-94-3. In its pure form, it is typically described as a white to off-white solid, with a melting point in the range of 37-42 °C. This physical state is important for handling, storage, and formulation considerations. While sources may vary slightly, the consistent reporting of these properties by various chemical databases and manufacturers underscores its well-defined nature.
The synthesis of 2-(p-Tolyl)propionic acid can be achieved through several routes, often starting from readily available aromatic compounds. Common precursors mentioned in literature include 4-methylstyrene or derivatives of toluene. For instance, hydrocarboxylation reactions or reactions involving carbon monoxide are typical industrial methods employed by manufacturers to produce this compound efficiently and in bulk. The precise synthetic route chosen by a manufacturer can influence the purity profile and cost of the final product.
As a carboxylic acid, 2-(p-Tolyl)propionic acid exhibits characteristic reactivity. It can undergo esterification, amide formation, and other reactions typical of this functional group. This reactivity makes it a versatile building block for more complex molecules. Its significance is particularly noted in its role as an intermediate in the synthesis of agrochemicals and as a critical reference standard for pharmaceutical impurities, such as Ibuprofen EP Impurity D. The pharmaceutical industry relies on high-purity standards like this to ensure the safety and quality of medications.
For those seeking to buy 2-(p-Tolyl)propionic acid, understanding these chemical properties is crucial for selecting the right supplier. Manufacturers will often provide detailed technical data sheets (TDS) that include information on solubility, stability, and safety, in addition to purity. When you inquire about pricing or availability, having this foundational chemical knowledge helps in communicating your needs effectively to a supplier. For example, knowing its solid form and melting point aids in logistics and storage planning.
In summary, 2-(p-Tolyl)propionic acid is a well-characterized organic compound with important applications. Its chemical structure, physical properties, and reactivity profile make it an indispensable component in various synthesis pathways. For industry professionals, partnering with a knowledgeable manufacturer ensures access to this compound with the required purity and detailed technical information, facilitating innovation and product development.
Perspectives & Insights
Core Pioneer 24
“It can undergo esterification, amide formation, and other reactions typical of this functional group.”
Silicon Explorer X
“Its significance is particularly noted in its role as an intermediate in the synthesis of agrochemicals and as a critical reference standard for pharmaceutical impurities, such as Ibuprofen EP Impurity D.”
Quantum Catalyst AI
“The pharmaceutical industry relies on high-purity standards like this to ensure the safety and quality of medications.”