Chloromethyl Pivalate, identified by its CAS number 18997-19-8, stands as a pivotal chemical intermediate within the pharmaceutical industry. Its significance stems from its versatile application in the synthesis of Active Pharmaceutical Ingredients (APIs), acting as a critical building block that enables the creation of complex and life-saving medications. As a reputable manufacturer and supplier, understanding the compound's properties and applications is key for procurement managers and R&D scientists looking to buy high-quality materials.

The chemical structure of Chloromethyl Pivalate lends itself to various synthetic pathways. It is notably employed in acylation reactions and serves as a valuable protecting reagent for amines, a crucial step in multi-stage organic synthesis. This reactivity makes it indispensable for creating prodrugs, such as the pivaloyloxy methyl ester of ofloxacin, and for synthesizing complex molecules like sulbactam pivoxil. For businesses seeking to optimize their R&D pipelines or ensure a stable supply chain for existing products, identifying a reliable manufacturer in China is paramount.

The compound is typically a clear, colorless to slightly yellow liquid, with properties that include a boiling point around 146-148 °C and a density of approximately 1.045 g/mL. Its miscibility with most organic solvents, while being immiscible with water, further defines its handling and application parameters. When considering the price of Chloromethyl Pivalate, factors such as purity, volume, and supplier reliability play a significant role. Ensuring high purity (often ≥99%) is critical for pharmaceutical applications to avoid unwanted side reactions or impurities in the final API.

For procurement professionals, sourcing this essential intermediate requires a focus on quality assurance, supply chain stability, and competitive pricing. Partnering with experienced chemical suppliers who can provide detailed product documentation, certificates of analysis, and consistent delivery schedules is vital. Companies looking to purchase Chloromethyl Pivalate in bulk should prioritize suppliers with a proven track record in the fine chemical and pharmaceutical intermediate sectors. This ensures not only the quality of the product but also the efficiency and reliability of their manufacturing operations.

In summary, Chloromethyl Pivalate is more than just a chemical compound; it is a key enabler of pharmaceutical innovation. By understanding its chemical properties, applications, and the importance of selecting a trustworthy supplier, businesses can effectively leverage this intermediate to advance their product development and manufacturing goals.