Understanding Choline Dihydrogen Citrate: A Chemical Profile for Formulators
For product formulators in the pharmaceutical and food industries, a deep understanding of chemical ingredients is fundamental to creating effective and safe products. Choline Dihydrogen Citrate (CAS 77-91-8) is a compound that warrants detailed examination due to its essential biological roles and diverse industrial applications. As a professional supplier and manufacturer, we aim to provide formulators with the comprehensive chemical profile needed to confidently integrate this ingredient into their formulations.
Choline Dihydrogen Citrate is a salt formed by the reaction of choline, a vital nutrient, with citric acid. Chemically, its molecular formula is C11H21NO8, with a molecular weight of approximately 295.29 g/mol. Its physical appearance is typically a white crystalline powder, which is easily soluble in water, facilitating its incorporation into aqueous formulations. The compound's hygroscopic nature means it absorbs moisture from the air, necessitating proper storage conditions, usually in tightly sealed containers in a dry environment. Understanding these properties is crucial for formulators when developing stable and effective products.
The key specifications for Choline Dihydrogen Citrate often include high purity, typically assaying between 98.0% and 101.0% on an anhydrous basis. Essential quality parameters that formulators should verify from their supplier include moisture content (not exceeding 0.25%), limits on heavy metals (≤20ppm), and residue on ignition (≤0.05%). The pH of a 10% solution typically ranges from 3.5 to 4.5, indicating its mildly acidic nature. These specifications ensure that the product is suitable for pharmaceutical and food applications, contributing to the safety and efficacy of the end product. When you plan to purchase Choline Dihydrogen Citrate, always request a Certificate of Analysis (COA) from your supplier.
The applications of Choline Dihydrogen Citrate are broad, stemming from choline's fundamental role in cellular metabolism. In pharmaceuticals, it's recognized for supporting liver health by facilitating fat transport and metabolism, and for its contribution to cognitive functions as a precursor to acetylcholine. Formulators may also find it useful in dietary supplements designed to enhance memory and concentration. In the food industry, it serves as a nutritional fortifier, boosting the choline content of various food products. Its low irritancy makes it a preferred alternative to other choline sources, particularly for products aimed at children and pregnant women.
For formulators seeking a reliable source to buy Choline Dihydrogen Citrate, partnering with an experienced manufacturer like ourselves ensures access to high-quality material backed by rigorous quality control. We provide detailed technical data and support to assist you in your formulation development. Contact us to obtain a product quote and to discuss your specific needs for this versatile chemical compound.
Perspectives & Insights
Silicon Analyst 88
“When you plan to purchase Choline Dihydrogen Citrate, always request a Certificate of Analysis (COA) from your supplier.”
Quantum Seeker Pro
“The applications of Choline Dihydrogen Citrate are broad, stemming from choline's fundamental role in cellular metabolism.”
Bio Reader 7
“In pharmaceuticals, it's recognized for supporting liver health by facilitating fat transport and metabolism, and for its contribution to cognitive functions as a precursor to acetylcholine.”