In the realm of organic chemistry, precise control over molecular stereochemistry is paramount. For researchers and chemists in the pharmaceutical and fine chemical industries, understanding key reagents like (DHQ)2PHAL (CAS 140924-50-1) is crucial. This article aims to shed light on its properties, applications, and the benefits of sourcing it from reliable manufacturers.

Chemical Profile of (DHQ)2PHAL

(DHQ)2PHAL, or Hydroquinine 1,4-phthalazinediyl diether, is recognized for its role as a chiral ligand. Sourced from dihydroquinine, it possesses specific physical and chemical characteristics, including a melting point typically around 178°C (with decomposition) and a notable optical activity, often reported as [α]22/D +336° in methanol. Its molecular formula is C48H54N6O4, with a molecular weight of approximately 778.98 g/mol. These precise specifications are vital for ensuring its efficacy in catalytic applications.

The Power of Asymmetric Dihydroxylation

The primary utility of (DHQ)2PHAL lies in its function as a ligand in the Sharpless Asymmetric Dihydroxylation (SAD) reaction. This highly effective method allows chemists to convert alkene double bonds into vicinal diols with remarkable control over stereochemistry. The resulting chiral diols are indispensable intermediates in the synthesis of a wide array of complex organic molecules, including pharmaceuticals, natural products, and fine chemicals. For professionals looking to buy (DHQ)2PHAL, understanding this application highlights its value in achieving enantioselective synthesis.

Sourcing (DHQ)2PHAL: A Strategic Move

For businesses requiring this specialized chemical, identifying a dependable (DHQ)2PHAL manufacturer is key. NINGBO INNO PHARMCHEM CO.,LTD. serves as a prime example of a supplier in China dedicated to providing high-quality pharmaceutical intermediates. When you purchase (DHQ)2PHAL from such a source, you benefit from competitive pricing and a consistent supply chain, critical for production continuity. The availability of detailed product specifications, such as CAS 140924-50-1, ensures you are acquiring the correct material for your intended application.

Ensuring Quality and Purity

When seeking a CAS 140924-50-1 supplier, quality assurance is non-negotiable. Reputable manufacturers will provide certifications detailing purity levels, typically achieved through techniques like High-Performance Liquid Chromatography (HPLC). Ensuring high enantiomeric excess (e.e.) is also paramount for its catalytic performance. By choosing a manufacturer with robust quality control systems, research scientists and procurement teams can confidently integrate (DHQ)2PHAL into their demanding synthetic procedures.

The importance of (DHQ)2PHAL in modern organic synthesis cannot be overstated. Its role in asymmetric dihydroxylation makes it a cornerstone for producing enantiomerically pure compounds, essential for the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a leading supplier, offering high-quality (DHQ)2PHAL to meet the diverse needs of global clients.