Understanding Diprophylline: Chemical Profile for Respiratory & Cardiovascular Health
Diprophylline, also known by its chemical name 7-(2,3-dihydroxypropyl)theophylline and CAS number 479-18-5, is a significant xanthine derivative that holds considerable importance in the pharmaceutical industry, particularly for its applications in respiratory and cardiovascular health. This compound's unique chemical structure and pharmacological profile make it a valuable intermediate for developing a range of therapeutic agents. NINGBO INNO PHARMCHEM CO.,LTD. is a key supplier of this high-purity pharmaceutical powder, supporting global health initiatives.
Chemically, Diprophylline is characterized by its a theophylline backbone modified with a 2,3-dihydroxypropyl group at the N-7 position. This structural modification contributes to its distinct pharmacological properties, including bronchodilation, vasodilation, and diuretic effects. Unlike theophylline, Diprophylline is excreted largely unchanged by the kidneys, suggesting a different metabolic pathway and potentially influencing its pharmacokinetic profile. Its molecular weight is approximately 254.24 g/mol, and it typically presents as a white crystalline powder, freely soluble in water.
The primary therapeutic application of Diprophylline lies in its role as a bronchodilator. It effectively relaxes the smooth muscles of the bronchi, thereby widening the airways and alleviating symptoms associated with obstructive airway diseases such as asthma, chronic bronchitis, and emphysema. This action is crucial for improving respiratory function and relieving breathlessness. The vasodilator properties of Diprophylline also contribute to its therapeutic utility, as they can improve blood flow and potentially benefit patients with co-existing cardiovascular conditions often seen in conjunction with severe respiratory diseases.
Furthermore, Diprophylline is noted for its superior gastrointestinal tolerability compared to other xanthine derivatives. This characteristic is highly valued in pharmaceutical formulation, as it allows for more consistent patient adherence to treatment regimens, a critical factor in managing chronic conditions. Pharmaceutical companies often seek out this specific intermediate when developing medications that require long-term use and a favorable side-effect profile.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing pharmaceutical-grade Diprophylline powder that meets stringent purity and quality specifications. As a reliable manufacturer and supplier, we ensure that our product is a consistent and high-quality raw material for your pharmaceutical needs. If you are looking to buy Diprophylline powder for your formulations, we offer competitive pricing and a commitment to excellence. Partner with us to access this vital pharmaceutical intermediate and contribute to better patient outcomes in respiratory and cardiovascular health.
Perspectives & Insights
Logic Thinker AI
“24 g/mol, and it typically presents as a white crystalline powder, freely soluble in water.”
Molecule Spark 2025
“The primary therapeutic application of Diprophylline lies in its role as a bronchodilator.”
Alpha Pioneer 01
“It effectively relaxes the smooth muscles of the bronchi, thereby widening the airways and alleviating symptoms associated with obstructive airway diseases such as asthma, chronic bronchitis, and emphysema.”