In the realm of biochemical and biophysical research, understanding the behavior of cellular membranes is fundamental. Artificial membranes, often constructed from purified lipids, serve as invaluable models for studying complex biological processes. Among the essential components for building these model systems is 1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine sodium salt, commonly known as DPPS-NA, with the CAS number 145849-32-7. As a dedicated supplier and manufacturer of high-quality biochemicals, we highlight the significance of this anionic phospholipid.

DPPS-NA is a diacylphosphatidylserine, characterized by two palmitic acid (C16:0) chains attached to the glycerol backbone and a serine headgroup carrying a negative charge at physiological pH. This anionic nature is crucial for its function in biological membranes, where it influences electrostatic interactions, membrane curvature, and signaling pathways. Its precise molecular structure and well-defined properties make it a preferred choice for scientists aiming to replicate specific membrane characteristics in vitro.

Researchers often buy DPPS-NA for its utility in creating biomimetic membranes. These synthetic lipid bilayers can be used to study protein-lipid interactions, ion channel function, membrane fusion, and the effects of various compounds on membrane integrity. The ability to precisely control the lipid composition, including the incorporation of DPPS-NA, allows for the isolation and investigation of specific membrane phenomena. For instance, its anionic charge can be used to mimic the inner leaflet of the plasma membrane or to study the influence of charged lipids on membrane phase behavior.

The chemical industry plays a vital role in supplying these specialized reagents. For research scientists, identifying reliable suppliers who offer high-purity DPPS-NA is paramount. A purity level of 99% ensures that the observed behavior in artificial membranes is attributable to DPPS-NA itself, rather than impurities. Whether purchasing for basic research or for more applied studies in areas like drug screening or diagnostics, consistent quality is key.

When considering the cost, the price of DPPS-NA will depend on the quantity and the supplier. Many manufacturers offer various pack sizes, catering to both small-scale laboratory experiments and larger research projects. It is advisable to request a quote from manufacturers and suppliers, especially when planning for sustained research or bulk requirements. Understanding the typical market price per gram can aid in budget allocation.

In summary, DPPS-NA is a fundamental anionic phospholipid that provides researchers with a powerful tool for constructing and studying artificial membrane systems. Its unique properties make it indispensable for investigations into membrane biophysics and biochemistry. By ensuring the procurement of high-purity DPPS-NA from reputable sources, scientific endeavors can achieve greater accuracy and deeper insights into cellular membrane functions.