Esomeprazole Magnesium Trihydrate, identified by CAS number 217087-09-7, plays a crucial role as a pharmaceutical intermediate in the synthesis of various medications, most notably proton pump inhibitors used to treat conditions related to excess stomach acid. As a chiral sulfoxide derivative, its precise chemical structure and high purity are essential for ensuring the efficacy and safety of the final Active Pharmaceutical Ingredient (API). For R&D scientists and procurement specialists, understanding the critical aspects of this compound is key when looking to buy it.

Chemical Properties and Significance

The material is typically presented as a white to off-white powder. Its molecular formula, 2C17H18N3O3S.Mg.3H2O, indicates its complex structure involving magnesium and trihydrate components, which are vital for its stability and handling. The purity, often specified as ≥98%, directly influences its suitability for pharmaceutical applications. A reliable manufacturer will provide detailed specifications and analytical data to confirm these properties. This ensures that when you purchase Esomeprazole Magnesium Trihydrate, you are acquiring material that meets industry standards.

Application in Pharmaceutical Manufacturing

The primary application of Esomeprazole Magnesium Trihydrate lies in its use as a precursor or intermediate in the production of esomeprazole, the S-isomer of omeprazole. Esomeprazole is a widely used medication for treating conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The synthesis process demands intermediates of exceptional quality to achieve the desired stereochemistry and purity of the final API. Therefore, sourcing from a reputable supplier with a proven track record in pharmaceutical intermediates is paramount.

Sourcing Considerations: The Manufacturer's Role

When considering where to buy Esomeprazole Magnesium Trihydrate, the origin and manufacturing practices of the supplier are critical. A manufacturer in China with a strong emphasis on quality control, adherence to Good Manufacturing Practices (GMP) principles where applicable, and transparent documentation will be your best choice. Understanding the price structure and requesting a detailed quote will help in making an informed decision. Partnering with a trusted supplier ensures not only the quality of the intermediate but also the reliability of your supply chain.

If your research or manufacturing requires Esomeprazole Magnesium Trihydrate, selecting a knowledgeable and quality-focused Chinese supplier is a strategic advantage. We are proud to be such a supplier, committed to delivering excellence in every batch.