Ethyl 3,3-Diethoxypropionate (CAS 10601-80-6) is a versatile organic compound widely recognized for its utility as a synthesis intermediate. Its chemical structure, featuring an ester group and two ethoxy groups attached to the same carbon, bestows upon it a unique reactivity profile. As a clear, colorless liquid, it is a favored reagent in numerous chemical transformations, particularly within the pharmaceutical and fine chemical industries. Understanding its synthesis and properties is key to leveraging its full potential.

The synthesis of Ethyl 3,3-Diethoxypropionate typically involves reactions utilizing readily available starting materials. One common method described in literature involves the reaction of 1,1,1-trichloro-4-ethoxy-3-buten-2-one with ethanol in the presence of a base, such as anhydrous potassium carbonate. This reaction proceeds under controlled conditions to yield the desired product. The efficiency and yield of such syntheses are often optimized by manufacturers to ensure economic viability and high purity, which is crucial for its downstream applications.

Key physical and chemical properties of Ethyl 3,3-Diethoxypropionate include its molecular formula C9H18O4 and a molecular weight of approximately 190.24 g/mol. Its boiling point is approximately 92-93 °C at 13 mmHg, indicating relatively low volatility under reduced pressure. The density is around 0.978 g/mL at 25 °C. These properties are important considerations for storage, handling, and reaction design. The compound is generally soluble in common organic solvents, further enhancing its versatility.

For professionals seeking to buy Ethyl 3,3-Diethoxypropionate, understanding these properties aids in selecting the appropriate grades and handling procedures. Reputable suppliers, particularly those acting as a manufacturer of Ethyl 3,3-Diethoxypropionate in regions like China, provide detailed technical data, including MSDS sheets, which outline safety precautions, storage conditions (often recommending storage in a cool, dry place, tightly sealed), and potential hazards. For instance, hazard statements might include skin, eye, and respiratory irritation, necessitating appropriate personal protective equipment during handling.

The applications stemming from these properties are extensive. Ethyl 3,3-Diethoxypropionate serves as a vital building block in the synthesis of pharmaceuticals, agrochemicals, and various fine chemicals. Its diethoxy group can be readily transformed or utilized in cyclization reactions, making it instrumental in constructing complex organic molecules. When exploring procurement options, buyers often request a quote for Ethyl 3,3-Diethoxypropionate, looking for a balance of quality and cost-effectiveness. Engaging with a trusted supplier of Ethyl 3,3-Diethoxypropionate ensures access to product information and reliable supply chains.

In conclusion, a thorough understanding of Ethyl 3,3-Diethoxypropionate's synthesis and chemical properties is fundamental for its effective utilization. By partnering with experienced manufacturers and suppliers, researchers and industrial chemists can confidently integrate this important intermediate into their processes, driving innovation in chemical synthesis.