In the realm of fine chemicals and pharmaceutical manufacturing, the purity and precise specifications of raw materials are not merely guidelines but absolute necessities. Ethyl Cyanoacetate (CAS 105-56-6), a compound widely utilized as a versatile organic intermediate, is no exception. Understanding its quality parameters is crucial for ensuring the efficacy and safety of downstream products. This article outlines the key specifications and purity levels that industrial buyers should look for when sourcing Ethyl Cyanoacetate.

Ethyl Cyanoacetate is typically supplied as a colorless liquid with a pleasant odor, boasting a molecular formula of C5H7NO2. The most critical specification for its industrial application, particularly in pharmaceutical synthesis and dye production, is its purity. Reputable manufacturers, especially those based in China, commonly guarantee a minimum purity of 99.00%. This high purity level ensures minimal interference from by-products and contaminants, which is vital for complex chemical reactions where even trace impurities can affect yield, product quality, or catalytic efficiency.

Beyond overall purity, several other parameters are important. Water content is another key specification, often kept to a maximum of 0.1%. High water content can interfere with certain reactions, especially those sensitive to moisture, and can also affect the stability of the product during storage. The density, typically around 1.063 g/mL at 25°C, and boiling point, in the range of 208-210°C, are also important physical properties that manufacturers will provide to confirm product identity and consistency.

For users involved in organic synthesis, the chemical reactivity of Ethyl Cyanoacetate is inherently linked to its purity. Its functional groups—an ester and a nitrile—attached to an active methylene group, make it a powerful synthon for Knoevenagel condensations, Michael additions, and the synthesis of heterocyclic compounds. Ensuring a high purity batch means that these reactions proceed predictably and efficiently, leading to higher yields and more consistent product outcomes.

When selecting an Ethyl Cyanoacetate supplier, it is essential to request a Certificate of Analysis (CoA) for each batch. This document details the specific analytical results for purity, water content, and other relevant parameters, confirming that the product meets the stated specifications. For companies looking to buy Ethyl Cyanoacetate, especially in bulk, establishing a relationship with a manufacturer that consistently delivers material meeting these high standards is paramount for maintaining product integrity and operational efficiency.

In summary, adhering to stringent purity and specification standards is fundamental when using Ethyl Cyanoacetate in industrial applications. By prioritizing high purity (≥99.00%), low water content, and other key physical and chemical properties, and by verifying these through CoAs from reliable suppliers, manufacturers can effectively leverage the synthetic potential of this crucial organic intermediate.