Fenoxazoline Hydrochloride (CAS 21370-21-8) is a compound with significant pharmacological relevance, primarily functioning as a nasal decongestant. Its effectiveness is rooted in its specific mechanism of action and well-defined chemical properties, making it a subject of interest in pharmaceutical science. This article aims to provide a detailed look into these scientific aspects, offering insights for professionals seeking to understand and utilize this chemical compound.

The primary mechanism of action for Fenoxazoline Hydrochloride involves its role as an alpha-adrenergic agonist. It selectively binds to and stimulates alpha-1 adrenergic receptors located on the smooth muscle cells of blood vessels within the nasal mucosa. This stimulation leads to vasoconstriction, a narrowing of the blood vessels. The result is a reduction in blood flow to the nasal tissues, which effectively decreases swelling and alleviates nasal congestion. This targeted action makes it a highly effective topical decongestant, providing relief from symptoms associated with colds, allergies, and sinusitis.

From a chemical perspective, Fenoxazoline Hydrochloride is characterized by its molecular formula C13H18N2O. It typically presents as a white to off-white crystalline powder. A key property is its solubility, being soluble in water and organic solvents like ethanol, which facilitates its incorporation into various pharmaceutical formulations, such as nasal sprays and drops. Understanding these chemical properties is crucial for formulation development and ensuring the stability and efficacy of the final product.

The synthesis of Fenoxazoline Hydrochloride is a carefully controlled chemical process. As a manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent manufacturing protocols to produce high-quality Fenoxazoline Hydrochloride. The synthesis often begins with 2-isopropylphenol, reacting with formaldehyde and ethylenediamine, culminating in the hydrochloride salt. This process ensures the intermediate meets the purity standards required for pharmaceutical use. Researchers and manufacturers seeking to buy Fenoxazoline Hydrochloride can rely on suppliers who prioritize precision in chemical synthesis.

The chemical stability of Fenoxazoline Hydrochloride under various conditions is also an important consideration. While sensitive to certain stress conditions, its formulation as a hydrochloride salt generally imparts good stability for its intended applications. This compound’s predictable behavior and efficacy make it a valuable asset in the pharmaceutical industry, and as a leading supplier, we are committed to providing this essential intermediate with the highest standards of quality and reliability.