Fmoc-3-(2-Naphthyl)-D-alanine, identified by CAS number 138774-94-4, is a remarkable compound with a unique set of properties that make it invaluable in specialized chemical synthesis. As supplied by NINGBO INNO PHARMCHEM CO.,LTD., this off-white crystalline powder possesses a defined melting point of approximately 191°C, indicating its stable solid form under standard conditions. Its molecular formula, C28H23NO4, and molecular weight of 437.49 g/mol underscore its complex organic structure. The compound exhibits slight solubility in water but is soluble in various organic solvents like Chloroform, DMF, and DMSO, a characteristic that is crucial for its effective use in solution-phase reactions and analytical procedures. Researchers can purchase Fmoc-3-(2-Naphthyl)-D-alanine to leverage these properties in intricate synthetic pathways.

The primary utility of Fmoc-3-(2-Naphthyl)-D-alanine lies in its role as an advanced building block. Its structure combines the robust Fmoc protecting group with a D-alanine backbone featuring a naphthyl substituent. This combination is particularly advantageous in peptide synthesis, where the Fmoc group facilitates controlled chain elongation, and the naphthyl moiety can impart specific conformational or binding properties to the final peptide sequence. The compound's predicted pKa of 3.77±0.30 also provides insight into its behavior in different pH environments, which is important for reaction optimization. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this reagent is available with high purity, enabling reproducible and reliable outcomes in demanding chemical synthesis projects.

Beyond peptide synthesis, Fmoc-3-(2-Naphthyl)-D-alanine serves as a critical intermediate in the preparation of various bioactive molecules. Its application in developing inhibitors for proteins like BRCA1 highlights its importance in medicinal chemistry and the pharmaceutical industry. The availability of this compound from NINGBO INNO PHARMCHEM CO.,LTD. facilitates research into novel therapeutics, particularly in areas like oncology. Understanding the chemical and physical properties of Fmoc-3-(2-Naphthyl)-D-alanine is key to unlocking its full potential, and NINGBO INNO PHARMCHEM CO.,LTD. is a reliable source for this essential chemical synthesis tool.