In the realm of organic chemistry and especially in the field of peptide synthesis, understanding the properties and applications of key intermediates is crucial for efficient and successful outcomes. Fmoc-Glu(OBut)-ODhbt, a derivative of glutamic acid, is one such critical compound. This article aims to provide a detailed overview of Fmoc-Glu(OBut)-ODhbt, covering its chemical characteristics, its indispensable role in peptide synthesis, and practical advice for buyers looking to source this material from reputable manufacturers and suppliers.

Fmoc-Glu(OBut)-ODhbt is a white powder with the CAS number 114119-86-7. Its molecular formula is C31H30N4O7, and its molecular weight is approximately 570.59 g/mol. The compound features an Fmoc-protected alpha-amino group and a tert-butyl ester protecting the side-chain carboxyl group, coupled with an N-hydroxysuccinimide (NHS) ester on the side chain for enhanced reactivity. This specific structural configuration makes it an ideal building block in solid-phase peptide synthesis (SPPS) for introducing glutamic acid residues. The tert-butyl ester is cleaved under acidic conditions typically used at the end of SPPS, while the Fmoc group is removed using basic conditions during the synthesis cycle.

The primary application of Fmoc-Glu(OBut)-ODhbt is in the synthesis of peptides, where it enables the controlled incorporation of glutamic acid. Glutamic acid is a non-essential amino acid that plays vital roles in protein structure and function, and its derivatives are frequently found in bioactive peptides and proteins. By using Fmoc-Glu(OBut)-ODhbt, researchers can efficiently synthesize peptides for various applications, including drug discovery, development of diagnostic tools, and creation of biomaterials. As a leading manufacturer and supplier, we ensure the high purity of this compound, which is essential for preventing side reactions and achieving the desired peptide sequence with high fidelity. Our pricing reflects our commitment to providing quality reagents at competitive rates.

For procurement professionals and R&D scientists, sourcing Fmoc-Glu(OBut)-ODhbt involves selecting a supplier that can guarantee both quality and reliability. Our manufacturing facilities in China are equipped with advanced technology and adhere to strict quality management systems. This allows us to consistently produce Fmoc-Glu(OBut)-ODhbt that meets international standards. We encourage potential buyers to request a quote for our product. Understanding the specifications and recommended usage of Fmoc-Glu(OBut)-ODhbt, along with the supplier's track record, will facilitate informed purchasing decisions. We are confident that our offering will meet and exceed your expectations for this crucial peptide synthesis reagent.

In conclusion, Fmoc-Glu(OBut)-ODhbt is an indispensable tool for anyone involved in peptide synthesis. Its well-defined chemical properties and effectiveness in SPPS make it a valuable asset in pharmaceutical research, chemical synthesis, and biotechnology. We are dedicated to being a premier supplier, offering high-purity Fmoc-Glu(OBut)-ODhbt at competitive prices. Contact us to learn more about our products and how we can support your chemical needs.