For chemists and researchers involved in peptide synthesis and organic chemistry, a deep understanding of key reagents and their properties is essential for successful outcomes. Fmoc-Trp(Boc)-OH, chemically known as N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-in-t-butyloxycarbonyl-L-tryptophan, is a vital derivative that facilitates efficient and clean peptide chain elongation. This article aims to provide a comprehensive overview of its characteristics and applications, highlighting why it's a preferred choice for many synthetic chemists. As a dedicated manufacturer and supplier of fine chemical intermediates, we provide detailed information on this product to aid your research and purchasing decisions.

Fmoc-Trp(Boc)-OH is characterized by its specific chemical structure, which includes the Fmoc protecting group on the alpha-amino group and the Boc protecting group on the indole nitrogen of tryptophan. This dual protection strategy is critical for its utility in Solid-Phase Peptide Synthesis (SPPS). The Fmoc group allows for base-labile deprotection, a common method in modern SPPS, while the Boc group on the indole side chain offers enhanced stability against acidic conditions and prevents side reactions during cleavage. Typically supplied as a white to off-white crystalline powder, it has a defined melting point of 86-90°C and a molecular weight of 526.6 g/mol, indicating a high degree of purity. If you are looking to buy Fmoc-Trp(Boc)-OH, understanding these specifications is key to ensuring it meets your project requirements.

The principal application of Fmoc-Trp(Boc)-OH lies in the synthesis of peptides where tryptophan is a component. Its protected nature minimizes the formation of undesired byproducts, such as those resulting from the alkylation of the indole ring by reactive species generated during peptide cleavage. This results in peptides with higher purity and improved yields, making it an indispensable reagent for both academic research and industrial production. For laboratories seeking to purchase this compound, identifying a reliable supplier that consistently provides high-purity material is paramount. We pride ourselves on being a leading manufacturer and supplier of these critical chemical intermediates.

When considering the cost and availability, sourcing Fmoc-Trp(Boc)-OH from experienced manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., can provide a strategic advantage. We focus on delivering exceptional quality at competitive wholesale prices. Whether you are a researcher needing small quantities or a production facility requiring bulk orders, our commitment to quality control and efficient logistics ensures you receive a dependable product. Explore our offerings and discover why we are a preferred partner for chemists worldwide seeking high-performance amino acid derivatives for their synthesis needs.