The journey from raw materials to finished pharmaceuticals is complex, with each intermediate playing a crucial role. 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate, identified by CAS number 122111-11-9 and often referred to as Gemcitabine Intermediate T8, is one such indispensable compound. Its significance lies in its direct application in the synthesis of Gemcitabine, a vital chemotherapeutic agent.

For professionals in the pharmaceutical sector, understanding the chemical identity and properties of intermediates like T8 is fundamental. This molecule is a difluorinated pentofuranose derivative, featuring benzoate and methanesulfonate ester groups. Its precise chemical structure is critical for the subsequent stereoselective reactions required for Gemcitabine formation. When seeking to buy Gemcitabine Intermediate T8, paying attention to its molecular formula (C20H18F2O8S) and molecular weight (456.41) provides foundational knowledge.

The synthesis of Gemcitabine is a multi-step process, and the quality of the starting intermediates directly impacts the overall yield and purity of the final Active Pharmaceutical Ingredient (API). Gemcitabine Intermediate T8 serves as a key precursor, embodying much of the structural complexity required for the nucleoside analog. Its role highlights why sourcing from a reliable manufacturer with stringent quality controls is non-negotiable. As a leading supplier in China, we ensure that our intermediate meets the exact specifications required by the pharmaceutical industry.

Key quality parameters for this intermediate include its appearance, typically described as a brown liquid or solid depending on specific form and purity, and its assay. Purity levels, often cited as ≥98% or ≥99%, are vital. Furthermore, the isomeric purity (distinguishing between alpha and beta isomers) is a critical factor that can influence the success of downstream reactions. Procurement managers and research scientists should always request detailed analytical data from their chosen suppliers.

Engaging with a reputable manufacturer like ourselves means gaining access to consistent quality and competitive price points. We are dedicated to providing this essential pharmaceutical intermediate, supporting the global supply of Gemcitabine. Whether you are conducting early-stage research or scaling up for commercial production, our capabilities as a dedicated supplier ensure you receive a high-quality product that meets your exact needs.