Understanding Granzyme B: A Key Enzyme in Apoptosis and Immune Response
Granzyme B, identified by its CAS number 143180-74-9, is a fascinating and powerful enzyme with significant implications in both fundamental biological processes and advanced research. As a leading enzyme manufacturer, we are dedicated to providing high-quality Granzyme B to researchers worldwide. This serine protease is primarily produced by cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, making it a cornerstone of the adaptive and innate immune systems.
The primary function of Granzyme B is to induce apoptosis, or programmed cell death, in target cells. This mechanism is critical for eliminating virus-infected cells, tumor cells, and for regulating immune responses, thereby preventing autoimmune diseases. When CTLs and NK cells detect compromised or foreign cells, they release granules containing perforin and Granzyme B. Perforin forms pores in the target cell membrane, allowing Granzyme B to enter and initiate a cascade of events leading to cell death. This makes Granzyme B an indispensable tool for scientists studying cell death pathways, cancer immunology, and infectious diseases.
For researchers looking to buy granzyme b enzyme, understanding its applications is key. It's widely used in apoptosis research to model and study cell death mechanisms in vitro. Furthermore, its role in immune surveillance makes it valuable in oncology research, particularly in developing immunotherapies. Diagnostic laboratories also utilize Granzyme B in various assays, contributing to advancements in disease detection and prognosis.
As a reputable supplier in China, we ensure that our Granzyme B is of the highest purity and activity. We offer competitive granzyme b price options for both research and bulk purchases, catering to the diverse needs of our clients. Our commitment extends beyond just supplying a product; we aim to be a reliable partner in your scientific endeavors. Whether you are conducting complex immunological studies or developing cutting-edge diagnostic tools, choosing a dependable manufacturer for your biochemicals is paramount. We provide comprehensive technical data and support to ensure you get the most out of your purchase.
When considering where to purchase granzyme b, look for a supplier that prioritizes quality, consistency, and customer service. Our extensive experience in biochemical production positions us as a trusted source for Granzyme B (CAS 143180-74-9), empowering scientific discovery and innovation.
Perspectives & Insights
Alpha Spark Labs
“This serine protease is primarily produced by cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, making it a cornerstone of the adaptive and innate immune systems.”
Future Pioneer 88
“The primary function of Granzyme B is to induce apoptosis, or programmed cell death, in target cells.”
Core Explorer Pro
“This mechanism is critical for eliminating virus-infected cells, tumor cells, and for regulating immune responses, thereby preventing autoimmune diseases.”