Grignard reagents represent a cornerstone of modern organic chemistry, enabling the formation of new carbon-carbon bonds with remarkable efficiency. Among these powerful organometallic compounds, Ethylmagnesium Bromide (CAS 925-90-6) stands out as a widely utilized and versatile example. For chemists in R&D and procurement specialists looking to buy this reagent, understanding its characteristics, applications, and how to source it reliably is essential.

Ethylmagnesium Bromide is typically encountered as a solution in ethereal solvents like diethyl ether or tetrahydrofuran (THF). Its defining feature is the highly polar carbon-magnesium bond, which imparts significant nucleophilic character to the ethyl group. This reactivity allows it to readily attack electrophilic centers, making it a powerful tool for synthesis. The reagent's appearance is usually described as a grey to brown liquid, and its quality is often assessed by its assay, with high purity grades (e.g., 99.5% MIN) being preferred for critical applications like pharmaceutical synthesis.

While Grignard reagents are often prepared fresh due to their sensitivity to moisture and air, commercially available, high-quality preparations are readily accessible. When procurement managers are sourcing Ethylmagnesium Bromide, they should prioritize suppliers who can provide comprehensive technical data, including specifications, safety sheets (SDS/TDS), and information on their manufacturing processes. Companies that adhere to international standards such as USP, BP, EP, and FCC, and possess certifications like GMP and SGS, are particularly valuable partners. These manufacturers, often found in regions like China, can offer competitive pricing and a consistent supply of this vital chemical.

The utility of Ethylmagnesium Bromide extends to various fields, including the synthesis of complex organic molecules, intermediates for agrochemicals, and notably, pharmaceuticals. Its role in lipid chemistry, for instance, in the regiospecific analysis of triacylglycerols (TAG), highlights its precision. For research scientists, understanding how to effectively use Ethylmagnesium Bromide, including proper handling under inert atmospheres, is key to successful experimental outcomes.

In conclusion, Ethylmagnesium Bromide is a vital reagent for any synthetic chemist. By selecting a reputable manufacturer and supplier, particularly from China, and ensuring the reagent meets the required assay and purity standards, buyers can confidently integrate it into their synthesis workflows. Consider obtaining a quote from trusted suppliers to ensure you have a reliable source for your Ethylmagnesium Bromide needs.