Heparanase, specifically Heparanase I (CAS 9025-39-2), is a crucial enzyme that plays a significant role in various biological processes, most notably in the context of cancer research. Its primary function involves the degradation of heparan sulfate, a complex polysaccharide found in the extracellular matrix (ECM) and on cell surfaces. This enzymatic activity is central to understanding how cancer cells invade surrounding tissues and metastasize to distant sites.

The extracellular matrix provides structural support and regulates cellular functions. However, in the process of tumorigenesis, the aberrant remodeling of the ECM is a hallmark. Heparanase is the sole mammalian enzyme capable of cleaving heparan sulfate chains, thereby liberating sequestered growth factors and cytokines. This action can promote angiogenesis, influence immune cell migration, and drive tumor progression.

For researchers and pharmaceutical developers, accessing a high-quality source of Heparanase I is paramount. NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable manufacturer and supplier of this vital enzyme, offering Heparinase I with a purity of 99%. Sourcing this enzyme from a reputable manufacturer in China ensures that your experiments are based on reliable and consistent materials, crucial for valid scientific outcomes and the development of effective therapeutic strategies.

The implications of Heparanase I in cancer are profound. Studies have linked its overexpression to increased tumor growth, invasion, and metastasis in various cancer types. By understanding the mechanism of heparanase activity, scientists aim to develop targeted therapies that can inhibit its function, potentially halting or slowing down the spread of cancer. If you are looking to buy Heparinase I for your research or pharmaceutical applications, consider NINGBO INNO PHARMCHEM CO.,LTD. as your trusted supplier for high-purity enzyme.

As a leading supplier, we are dedicated to supporting scientific advancement by providing essential biochemicals. Our commitment to quality assurance means you can be confident in the performance of our Heparinase I. We invite you to contact us for pricing and to discuss your bulk purchase needs for this critical enzyme.