Hydrazine hydrochloride and its derivatives are foundational reagents in organic chemistry, playing a crucial role in the synthesis of a wide array of organic compounds, including pharmaceuticals, agrochemicals, and dyes. As a chemist, understanding the reactivity and application scope of these molecules is essential for successful synthesis design. This article delves into the properties and synthetic utility of hydrazine hydrochlorides, with a specific focus on 4-Benzyloxyphenylhydrazine Hydrochloride (CAS: 52068-30-1).

Hydrazine hydrochlorides, characterized by the presence of a -NHNH2 group protonated by HCl, offer enhanced stability and ease of handling compared to free hydrazines. This salt form often presents as crystalline solids, making them convenient for weighing and dispensing in laboratory settings. For 4-Benzyloxyphenylhydrazine Hydrochloride, its typical appearance as a cream to brown fluffy powder, with a melting point in the range of 187-189°C, is indicative of its crystalline nature. These physical properties are important considerations for researchers when planning synthetic procedures.

The synthetic utility of hydrazine hydrochlorides stems from the nucleophilic nature of the nitrogen atoms. They readily participate in condensation reactions with carbonyl compounds (aldehydes and ketones) to form hydrazones, which are key intermediates in reactions like the Fischer indole synthesis. Furthermore, they can be used in the preparation of heterocyclic compounds such as pyrazoles and triazoles, which are common structural motifs in many biologically active molecules. When seeking to buy these reagents, manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure high purity (often ≥97%) for reliable reaction outcomes.

Researchers often look for specific terms such as 'buy 4-benzyloxyphenylhydrazine hydrochloride' or 'hydrazine hydrochloride chemical supplier'. The presence of the benzyloxy group in 4-Benzyloxyphenylhydrazine Hydrochloride introduces additional functionality, allowing for further modifications or acting as a protecting group during multi-step syntheses. Its role as a pharmaceutical intermediate is significant, contributing to the construction of complex molecular frameworks essential for API development. Partnering with a supplier like NINGBO INNO PHARMCHEM CO.,LTD. guarantees access to this vital reagent.

For chemists and researchers requiring reliable sources of hydrazine hydrochlorides and related intermediates, NINGBO INNO PHARMCHEM CO.,LTD. stands ready to supply high-quality products. Inquire about pricing and availability to support your ongoing synthetic chemistry projects.